Peculiar features of life quality in patients with type 2 diabetes mellitus and postmenopausal osteoporosis

Aim. To study the peculiarities of the quality of life in patients with type 2 diabetes mellitus (DM2) and postmenopausal osteoporosis (PO).

Materials and methods. 104 postmenopausal women aged 49–67 were examined. They were divided into 3 groups: group 1 (38 persons) – patients with DM2 and PO, group 2 (24 persons) – patients with PO, group 3 (42 persons) – postmenopausal patients with DM2 without any osteoporosis signs. Their quality of life was assessed using SF-36 survey, sensations of pain – with four-component visual analogue scale.

Results. Physical component of health (PH) was statistically significantly lower in DM2 and PO group. Most patients of this group had decreased psychical component of health. In DM2 and PO group as compared with PO group statistically significantly lower values according to physical status-conditioned role functioning scales (RP) (p = 0,018), emotional status-conditioned role functioning (p = 0,028), PH (p = 0,038) were detected. When compared with DM2 group, physical functioning (p = 0,04), RP (p = 0,014), pain intensity (p = 0,049), PH (p = 0,014) appeared to be statistically significantly lower. The factors, negatively influencing the quality of life in patients of DM2 and PO group were the following: remoteness of diabetes, comorbidity, level of pain sensations, presence of diabetic polyneuropathy, insulin therapy in treatment, unsatisfactory glycemic control.

Conclusions. Osteoporosis in patients with type 2 diabetes mellitus worsens their quality of life, in particular at the expense of elevated intensity of pain sensations.