Cardiac magnetic resonance imaging in patients with history of COVID-19
- Authors: Maksimova A.S.1, Ryumshina N.I.1, Shelkovnikova T.A.1, Mochula O.V.1, Anfinogenova N.D.1, Ussov V.Y.1
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Affiliations:
- Tomsk National Research Medical Center, Cardiology Research Institute
- Issue: Vol 4, No 3 (2023)
- Pages: 280-291
- Section: Original Study Articles
- URL: https://journals.rcsi.science/DD/article/view/254069
- DOI: https://doi.org/10.17816/DD494103
- ID: 254069
Cite item
Abstract
BACKGROUND: Myocarditis is among the most common complications arising from coronavirus infection (COVID-19).
AIM: This study aims to find the differences in the patterns of myocardial injury between patients who had COVID-19 and those from the pre-pandemic period, as determined by contrast-enhanced cardiac magnetic resonance imaging.
MATERIALS AND METHODS: The study encompassed a retrospective analysis of 47 patients who underwent contrast-enhanced cardiac magnetic resonance imaging to rule out acute myocarditis. Group 1 comprised 34 patients with a confirmed history of COVID-19 through PCR testing (nasal and/or throat swabs), while Group 2 comprised 13 individuals who underwent contrast-enhanced cardiac magnetic resonance imaging in 2017 prior to the onset of the COVID-19 pandemic. All patients enrolled in the study had clinical manifestation of cardiac injury without signs of coronary artery disease as an underlying cause of condition.
RESULTS: The mean time from the onset of heart symptoms to the administration of contrast-enhanced cardiac magnetic resonance imaging was 166 days. In group 1, a decrease in exercise tolerance was observed in 77% of patients, and 14 (42%), 30 (88%), and 28 (85%) of patients complained of chest pain, shortness of breath, and heart palpitations, respectively. In group 2, four patients (30%) had dyspnea, nine patients (69%) complained of chest pain, and six patients (46%) had heart palpitations and/or feeling of arrhythmia. Myocardial injury in group 1 was more generalized. The third of them had displayed preserved increased pulmonary vascularity and pleural effusion. Within group 1, men had significantly lower left ventricular ejection fraction, lower values of global longitudinal deformation, and higher values of left atrial function compared with the corresponding parameters in women. Differences in women were found only in the number of the affected segments in the left ventricular myocardium.
CONCLUSION: SARS-CoV-2 virus caused extended myocardial injury, affecting a significant number of myocardial segments. Men had more frequent postinflammatory complications, characterized by abnormal function of the left ventricle and left atrium. Obtained results require continuous efforts for further assessment of long-term consequences of previous COVID-19 to the cardiovascular system. In this regard, contrast-enhanced cardiac magnetic resonance imaging may represent a sensitive imaging tool for the assessment of cardiac injury severity.
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##article.viewOnOriginalSite##About the authors
Aleksandra S. Maksimova
Tomsk National Research Medical Center, Cardiology Research Institute
Email: asmaximova@yandex.ru
ORCID iD: 0000-0002-4871-3283
SPIN-code: 2879-9550
MD, Cand. Sci. (Med.)
Russian Federation, TomskNadezhda I. Ryumshina
Tomsk National Research Medical Center, Cardiology Research Institute
Author for correspondence.
Email: n.rumshina@list.ru
ORCID iD: 0000-0002-6158-026X
SPIN-code: 6555-8937
MD, Cand. Sci. (Med.)
Russian Federation, TomskTatiana A. Shelkovnikova
Tomsk National Research Medical Center, Cardiology Research Institute
Email: fflly@mail.ru
ORCID iD: 0000-0001-8089-2851
SPIN-code: 1826-7850
MD, Cand. Sci. (Med.)
Russian Federation, TomskOlga V. Mochula
Tomsk National Research Medical Center, Cardiology Research Institute
Email: mochula.olga@gmail.com
ORCID iD: 0000-0002-7502-7502
SPIN-code: 3712-8492
MD, Cand. Sci. (Med.)
Russian Federation, TomskNina D. Anfinogenova
Tomsk National Research Medical Center, Cardiology Research Institute
Email: cardio.intl@gmail.com
ORCID iD: 0000-0003-1106-0730
SPIN-code: 6784-5440
MD, Dr. Sci. (Med.)
Russian Federation, TomskVladimir Yu. Ussov
Tomsk National Research Medical Center, Cardiology Research Institute
Email: ussov1962@yandex.ru
ORCID iD: 0000-0002-7352-6068
SPIN-code: 1299-2074
MD, Dr. Sci. (Med.), Professor
Russian Federation, TomskReferences
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