Osteopoikilosis in the ribs, pelvic region and spine: a case report

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Abstract

Osteopoikilosis is a rare inherited benign bone dysplasia incidentally found on radiological exams. It is characterized by a specific radiological pattern: diffuse, round or oval, symmetrically shaped sclerotic bone areas distributed throughout the skeleton. It is essential to do a correct diagnosis because these lesions could be easily confused with bone metastasis.

We reported a case of an osteopoikilosis patient presenting to our clinic with transient loss of consciousness and without any numbness, tingling and weakness in the legs or other parts of the body. The computed tomography scan showed multiple small sclerotic foci bone islands, scattered throughout the thoracic and lumbar spine, ribs, pelvic bone, sacrum and bilateral proximal femur. No significant increase in the activity was detected in technetium-99m whole-body bone scintigraphy. The patient was diagnosed with characteristic radiological findings of osteopoikilosis and was followed up.

About the authors

Maria Teresa Paparella

Department of Clinical and Experimental Medicine, Foggia University School of Medicine

Email: mt.paparella@gmail.com
ORCID iD: 0000-0003-2573-9509

MD

Italy, Viale L. Pinto 1, 71121, Foggia

Ilaria Gangai

Department of Clinical and Experimental Medicine, Foggia University School of Medicine

Email: hilary_ps@libero.it
ORCID iD: 0000-0001-9594-4810

MD

Italy, Viale L. Pinto 1, 71121, Foggia

Chiara Porro

Department of Clinical and Experimental Medicine, Foggia University School of Medicine

Email: chiara.porro@unifg.it
ORCID iD: 0000-0002-7526-6968

MD

Italy, Viale L. Pinto 1, 71121, Foggia

Laura Eusebi

Radiology Unit, Carlo Urbani

Email: lauraeu@virgilio.it
ORCID iD: 0000-0002-4172-5126

MD

Italy, Jesi

Ferdinando Silveri

Rheumatology Unit, University of Ancona

Email: fsilveri@libero.it
ORCID iD: 0000-0002-7847-245X

MD

Italy, Ancona

Aldo Cammarota

IRCCS-CROB

Email: aldo.cammarota@crob.it
ORCID iD: 0000-0003-4211-5140

MD

Italy, Rionero in Vulture

Giuseppe Guglielmi

Department of Clinical and Experimental Medicine, Foggia University School of Medicine; Radiology Unit, Barletta University Hospital

Author for correspondence.
Email: giuseppe.guglielmi@unifg.it
ORCID iD: 0000-0002-4325-8330

MD, Professor

Italy, Viale L. Pinto 1, 71121 Foggia; Foggia

References

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2. Fig. 1. Transverse cross-section computed tomography scan passing through the thoracic (a) and lumbar (b) spine. It shows numerous, well-defined, homogeneous, circular, hyperdense foci in spinous processes and vertebral arches.

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3. Fig. 2. Transverse cross-section computed tomography scan passing through the seventh rib. It shows numerous hyperdense lesions; these are well-circumscribed and are measured in millimeters.

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4. Fig. 3. Transverse cross-section computed tomography scan passing through the sacroiliac joints. It shows small, sclerotic, round opacities distributed symmetrically along sacrum, hip bone, and sacroiliac joints.

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5. Fig. 4. Transverse cross-section computed tomography scan passing through the femoral head. It shows numerous hyperdense lesions that conform with the osteopoikilosis in the femoral head; lesions are well-circumscribed and are measured in millimeters.

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Copyright (c) 2022 Paparella M.T., Gangai I., Porro C., Eusebi L., Silveri F., Cammarota A., Guglielmi G.

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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