Synthesis of Chalcogen-Containing Nanocomposites of Selenium and Tellurium with Arabinogalactan and a Study of Their Toxic and Antimicrobial Properties
- Autores: Sosedova L.M.1,2, Rukavishnikov V.S.1,2, Sukhov B.G.1,3, Borovskii G.B.1,4, Titov E.A.1,2, Novikov M.A.1,2, Vokina V.A.1,2, Yakimova N.L.1,2, Lesnichaya M.V.1,3, Kon’kova T.V.1,3, Borovskaya M.K.1,4, Graskova I.A.1,4, Perfil’eva A.I.1,4, Trofimov B.A.3
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Afiliações:
- Irkutsk Scientific Center, Siberian Branch
- East-Siberian Institute of Medical and Environmental Research
- Favorsky Institute of Chemistry, Siberian Branch
- Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch
- Edição: Volume 13, Nº 5-6 (2018)
- Páginas: 290-294
- Seção: Materials of the Conference “Nanomaterials and Living Systems” (NLS-2018), Kazan, 2018
- URL: https://journals.rcsi.science/2635-1676/article/view/220533
- DOI: https://doi.org/10.1134/S1995078018030175
- ID: 220533
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Resumo
This paper reports the synthesis of nanocomposites of selenium and tellurium on a polymer matrix: arabinogalactan. Their physicochemical and biological properties are presented in detail. Studies of the parameters of acute toxicity and sex sensitivity to the nanocomposite of selenium and arabinogalactan show the following. The nanocomposite is characterized as a substance with a low acute toxicity hazard in the acute intragastric route of entry; no differences in the sex sensitivity of animals are revealed. The concentration dependences of the cytotoxicity of composites for human HEp-2 and ECV-304 cell cultures, as well as the green monkey kidney fibroblasts (Vero B), are studied during the investigation of biological properties of the nanocomposites of Te and Se with arabinogalactan. It is found that the Te and Se nanocomposites exhibit a different dependence of cytotoxicity on the concentration in all cultures studied. The nanocomposite of arabinogalactan with elemental selenium is shown to have a bactericidal effect against the causative agent of the ring rot of potato Clavibacter michiganensis subsp. sepedonicus.
Sobre autores
L. Sosedova
Irkutsk Scientific Center, Siberian Branch; East-Siberian Institute of Medical and Environmental Research
Autor responsável pela correspondência
Email: sosedlar@mail.ru
Rússia, Irkutsk, 664033; Angarsk, Irkutsk oblast, 665826
V. Rukavishnikov
Irkutsk Scientific Center, Siberian Branch; East-Siberian Institute of Medical and Environmental Research
Email: sosedlar@mail.ru
Rússia, Irkutsk, 664033; Angarsk, Irkutsk oblast, 665826
B. Sukhov
Irkutsk Scientific Center, Siberian Branch; Favorsky Institute of Chemistry, Siberian Branch
Email: sosedlar@mail.ru
Rússia, Irkutsk, 664033; Irkutsk, 664033
G. Borovskii
Irkutsk Scientific Center, Siberian Branch; Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch
Email: sosedlar@mail.ru
Rússia, Irkutsk, 664033; Irkutsk, 664033
E. Titov
Irkutsk Scientific Center, Siberian Branch; East-Siberian Institute of Medical and Environmental Research
Email: sosedlar@mail.ru
Rússia, Irkutsk, 664033; Angarsk, Irkutsk oblast, 665826
M. Novikov
Irkutsk Scientific Center, Siberian Branch; East-Siberian Institute of Medical and Environmental Research
Email: sosedlar@mail.ru
Rússia, Irkutsk, 664033; Angarsk, Irkutsk oblast, 665826
V. Vokina
Irkutsk Scientific Center, Siberian Branch; East-Siberian Institute of Medical and Environmental Research
Email: sosedlar@mail.ru
Rússia, Irkutsk, 664033; Angarsk, Irkutsk oblast, 665826
N. Yakimova
Irkutsk Scientific Center, Siberian Branch; East-Siberian Institute of Medical and Environmental Research
Email: sosedlar@mail.ru
Rússia, Irkutsk, 664033; Angarsk, Irkutsk oblast, 665826
M. Lesnichaya
Irkutsk Scientific Center, Siberian Branch; Favorsky Institute of Chemistry, Siberian Branch
Email: sosedlar@mail.ru
Rússia, Irkutsk, 664033; Irkutsk, 664033
T. Kon’kova
Irkutsk Scientific Center, Siberian Branch; Favorsky Institute of Chemistry, Siberian Branch
Email: sosedlar@mail.ru
Rússia, Irkutsk, 664033; Irkutsk, 664033
M. Borovskaya
Irkutsk Scientific Center, Siberian Branch; Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch
Email: sosedlar@mail.ru
Rússia, Irkutsk, 664033; Irkutsk, 664033
I. Graskova
Irkutsk Scientific Center, Siberian Branch; Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch
Email: sosedlar@mail.ru
Rússia, Irkutsk, 664033; Irkutsk, 664033
A. Perfil’eva
Irkutsk Scientific Center, Siberian Branch; Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch
Email: sosedlar@mail.ru
Rússia, Irkutsk, 664033; Irkutsk, 664033
B. Trofimov
Favorsky Institute of Chemistry, Siberian Branch
Email: sosedlar@mail.ru
Rússia, Irkutsk, 664033
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