Synthesis of Chalcogen-Containing Nanocomposites of Selenium and Tellurium with Arabinogalactan and a Study of Their Toxic and Antimicrobial Properties


Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Тек жазылушылар үшін

Аннотация

This paper reports the synthesis of nanocomposites of selenium and tellurium on a polymer matrix: arabinogalactan. Their physicochemical and biological properties are presented in detail. Studies of the parameters of acute toxicity and sex sensitivity to the nanocomposite of selenium and arabinogalactan show the following. The nanocomposite is characterized as a substance with a low acute toxicity hazard in the acute intragastric route of entry; no differences in the sex sensitivity of animals are revealed. The concentration dependences of the cytotoxicity of composites for human HEp-2 and ECV-304 cell cultures, as well as the green monkey kidney fibroblasts (Vero B), are studied during the investigation of biological properties of the nanocomposites of Te and Se with arabinogalactan. It is found that the Te and Se nanocomposites exhibit a different dependence of cytotoxicity on the concentration in all cultures studied. The nanocomposite of arabinogalactan with elemental selenium is shown to have a bactericidal effect against the causative agent of the ring rot of potato Clavibacter michiganensis subsp. sepedonicus.

Авторлар туралы

L. Sosedova

Irkutsk Scientific Center, Siberian Branch; East-Siberian Institute of Medical and Environmental Research

Хат алмасуға жауапты Автор.
Email: sosedlar@mail.ru
Ресей, Irkutsk, 664033; Angarsk, Irkutsk oblast, 665826

V. Rukavishnikov

Irkutsk Scientific Center, Siberian Branch; East-Siberian Institute of Medical and Environmental Research

Email: sosedlar@mail.ru
Ресей, Irkutsk, 664033; Angarsk, Irkutsk oblast, 665826

B. Sukhov

Irkutsk Scientific Center, Siberian Branch; Favorsky Institute of Chemistry, Siberian Branch

Email: sosedlar@mail.ru
Ресей, Irkutsk, 664033; Irkutsk, 664033

G. Borovskii

Irkutsk Scientific Center, Siberian Branch; Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch

Email: sosedlar@mail.ru
Ресей, Irkutsk, 664033; Irkutsk, 664033

E. Titov

Irkutsk Scientific Center, Siberian Branch; East-Siberian Institute of Medical and Environmental Research

Email: sosedlar@mail.ru
Ресей, Irkutsk, 664033; Angarsk, Irkutsk oblast, 665826

M. Novikov

Irkutsk Scientific Center, Siberian Branch; East-Siberian Institute of Medical and Environmental Research

Email: sosedlar@mail.ru
Ресей, Irkutsk, 664033; Angarsk, Irkutsk oblast, 665826

V. Vokina

Irkutsk Scientific Center, Siberian Branch; East-Siberian Institute of Medical and Environmental Research

Email: sosedlar@mail.ru
Ресей, Irkutsk, 664033; Angarsk, Irkutsk oblast, 665826

N. Yakimova

Irkutsk Scientific Center, Siberian Branch; East-Siberian Institute of Medical and Environmental Research

Email: sosedlar@mail.ru
Ресей, Irkutsk, 664033; Angarsk, Irkutsk oblast, 665826

M. Lesnichaya

Irkutsk Scientific Center, Siberian Branch; Favorsky Institute of Chemistry, Siberian Branch

Email: sosedlar@mail.ru
Ресей, Irkutsk, 664033; Irkutsk, 664033

T. Kon’kova

Irkutsk Scientific Center, Siberian Branch; Favorsky Institute of Chemistry, Siberian Branch

Email: sosedlar@mail.ru
Ресей, Irkutsk, 664033; Irkutsk, 664033

M. Borovskaya

Irkutsk Scientific Center, Siberian Branch; Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch

Email: sosedlar@mail.ru
Ресей, Irkutsk, 664033; Irkutsk, 664033

I. Graskova

Irkutsk Scientific Center, Siberian Branch; Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch

Email: sosedlar@mail.ru
Ресей, Irkutsk, 664033; Irkutsk, 664033

A. Perfil’eva

Irkutsk Scientific Center, Siberian Branch; Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch

Email: sosedlar@mail.ru
Ресей, Irkutsk, 664033; Irkutsk, 664033

B. Trofimov

Favorsky Institute of Chemistry, Siberian Branch

Email: sosedlar@mail.ru
Ресей, Irkutsk, 664033

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