Synthesis of Chalcogen-Containing Nanocomposites of Selenium and Tellurium with Arabinogalactan and a Study of Their Toxic and Antimicrobial Properties

L. M. Sosedova; V. S. Rukavishnikov; B. G. Sukhov; G. B. Borovskii; E. A. Titov; M. A. Novikov; V. A. Vokina; N. L. Yakimova; M. V. Lesnichaya; T. V. Kon’kova; M. K. Borovskaya; I. A. Graskova; A. I. Perfil’eva; B. A. Trofimov

doi:10.1134/S1995078018030175

Synthesis of Chalcogen-Containing Nanocomposites of Selenium and Tellurium with Arabinogalactan and a Study of Their Toxic and Antimicrobial Properties

作者: Sosedova L.M.¹^,2, Rukavishnikov V.S.¹^,2, Sukhov B.G.¹^,3, Borovskii G.B.¹^,4, Titov E.A.¹^,2, Novikov M.A.¹^,2, Vokina V.A.¹^,2, Yakimova N.L.¹^,2, Lesnichaya M.V.¹^,3, Kon’kova T.V.¹^,3, Borovskaya M.K.¹^,4, Graskova I.A.¹^,4, Perfil’eva A.I.¹^,4, Trofimov B.A.³
隶属关系:
1. Irkutsk Scientific Center, Siberian Branch
2. East-Siberian Institute of Medical and Environmental Research
3. Favorsky Institute of Chemistry, Siberian Branch
4. Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch
期: 卷 13, 编号 5-6 (2018)
页面: 290-294
栏目: Materials of the Conference “Nanomaterials and Living Systems” (NLS-2018), Kazan, 2018
URL: https://journals.rcsi.science/2635-1676/article/view/220533
DOI: https://doi.org/10.1134/S1995078018030175
ID: 220533

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This paper reports the synthesis of nanocomposites of selenium and tellurium on a polymer matrix: arabinogalactan. Their physicochemical and biological properties are presented in detail. Studies of the parameters of acute toxicity and sex sensitivity to the nanocomposite of selenium and arabinogalactan show the following. The nanocomposite is characterized as a substance with a low acute toxicity hazard in the acute intragastric route of entry; no differences in the sex sensitivity of animals are revealed. The concentration dependences of the cytotoxicity of composites for human HEp-2 and ECV-304 cell cultures, as well as the green monkey kidney fibroblasts (Vero B), are studied during the investigation of biological properties of the nanocomposites of Te and Se with arabinogalactan. It is found that the Te and Se nanocomposites exhibit a different dependence of cytotoxicity on the concentration in all cultures studied. The nanocomposite of arabinogalactan with elemental selenium is shown to have a bactericidal effect against the causative agent of the ring rot of potato Clavibacter michiganensis subsp. sepedonicus.

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Synthesis of Chalcogen-Containing Nanocomposites of Selenium and Tellurium with Arabinogalactan and a Study of Their Toxic and Antimicrobial Properties

全文:

详细

作者简介

L. Sosedova

V. Rukavishnikov

B. Sukhov

G. Borovskii

E. Titov

M. Novikov

V. Vokina

N. Yakimova

M. Lesnichaya

T. Kon’kova

M. Borovskaya

I. Graskova

A. Perfil’eva

B. Trofimov

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