Vol 13, No 1-2 (2013)
- Year: 2013
- Articles: 53
- URL: https://journals.rcsi.science/2410-3764/issue/view/1376
- DOI: https://doi.org/10.17816/2072-2354.2013.0.1-2
Articles
The current view on the problem of endothelial dysfunction in immune thrombocytopenic purpura (literature review)
Abstract
The article reviews the up-to-date views on the role of endothelial dysfunction in the development of hemorrhagic syndrome in immune thrombocytopenic purpura. The basic pathogenesis of endothelial dysfunction is presented. The questions of diagnosis of endothelial dysfunction and microcirculatory disturbances in patients with immune thrombocytopenic purpura are analyzed.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):8-13
8-13
Current diagnostic methods of monoclonal gammopathy (literature review)
Abstract
The article is a review of the clinical diagnostic and laboratory data obtained in different research laboratories. Criteria of diagnosis of various monoclonal gammopathy. Reflects current diagnostic laboratory methods. Particular attention is paid to the method of determination of free light chains of serum immunoglobulins by the "Freelight", which has a high sensitivity and specificity.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):14-16
14-16
Metabolic base of clinical manifestations in the patients with psoriasis
Abstract
The assessment of cellular composition of blood and metabolism in the patients with varying severity psoriasis is carried out. 52 patients are included in the research with average and heavy severity of psoriasis. Laboratory criteria of weight are revealed: the decrease of the contents osteocalcin and level increase parathyroid hormone, increase in quantity of leukocytes, speeds of subsidence of erythrocytes, the increase of concentration of hemoglobin in an erythrocyte. In the patients with psoriasis in the process of the increase of severity of a skin syndrome changes of system character accrue.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):17-21
17-21
Hemostatic system state in hemorrhagic vasculitis and genetic polymorphism: is there any connection?
Abstract
The published data on the changes of the hemostatic system in hemorrhagic vasculitis are surveyed. The effect of mutations of genes primarily responsible for hyperhomocysteinemia, on the course of hemorrhagic vasculitis is pathogenetically proved. Preliminary results of the research and MTHFR gene mutations MTRR in patients with this disease are shown. It was noted that at present there is no clear evidence of a statistically significant effect of mutations of the genes controlling the hemostatic system, on the course of hemorrhagic vasculitis, and the study of this question seems to be very promising.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):22-26
22-26
The development of the forecasting way of clinical manifestation dynamics of chronic virus hepatitis B during pathogenitic therapy in the hospital
Abstract
The investigation results concerning the development of the forecasting way of the chronic virus hepatitis B course based on the clinical and laboratory data registered during the hospitalization of the patient in the hospital are given in the article. The methodology data of drawing up the software of the forecasting procedure are stated. The developed way is shown to possess necessary operational characteristics for the application in practical health care: high sensitivity, specificity and predictive value.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):27-30
27-30
Characteristics of liver fibrosis stages in patients with HCV-infection based on the instrumental and histological research
Abstract
The work purpose is to compare data on a stage of liver fibrosis in patients with HCV-infection, obtained as a result of the ultrasonic and histological research, to give the comparative analysis of distribution of the patients depending on a stage of liver fibrosis treated during 2005-2012. In addition to directly measured ultrasonic structure parameters liver and spleen hemodynamics with calculated indicators were obtained: the portion of the evaluated section of liver and spleen lobes, and also their ratio. It is shown that the ultrasonic research executed on the modern equipment, including a dopplerography, in most cases (70–80%) allows specifying the degree of liver fibrosis without resorting to the histological verification.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):31-36
31-36
Features of colorectal intestine, occurs against a background polychemotherapy in hematological malignancies
Abstract
The purpose of our study is to define the role of apoptosis activity, molecules, Ki-67 and TLP in pathogenesis of colorectal pathology in the patients receiving polychemotherapy (PCT). The impairment of the colon mucosa in the hemoblastosis patients undergone PCT is believed to be associated with reduced cell proliferation and the decrease of the expression of Ki-67, increasing apoptosis activity cells of the colon and violation of cellular differentiation of expression molecules TLP.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):37-42
37-42
The comparative characteristic of the calculated method of estimated glomerular filtration rate in senile patients with chronic kidney disease
Abstract
The examination of 71 patients ranged from 75 to 90 years in age (mean age 83,3 ± 4,4 years) with chronic kidney disease (CKD) to compare the calculated methods of estimated glomerular filtration rate (GFR) from serum creatinine and cystatin C, and comparison performance indicators of the level of GFR with erythropoietin (EPO), and intact parathyroid hormone (iPTH). The data on the over-counting of the estimation of GFR from cystatin C with GFR above 60 ml/min/1, 73 m ² and underreporting of the estimation GFR by Cockcroft-Gault equation for creatinine clearance, especially at values below 45 ml/min/1,73 m².
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):43-49
43-49
The review of the cooperation of patients with bronchial asthma based on the instrument control estimation: GINA and ACQ-5
Abstract
In the article the cooperation of patients with bronchial asthma (BA) at various levels of control achievement is examined. Indicators of cooperation are estimated using the questionnaire ICBA - 50. 212 patients with bronchial asthma have been included in the research. All the patients have been divided into two groups depending on the tool of an estimation of control (GINA and ACQ-5). It has been established that the cooperation does not depend on tools of an estimation of control BA (GINA and ACQ-5), the level of its achievement and makes 62 %. The obtained data can improve the treatment BA efficiency.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):50-54
50-54
Current state of the endothelial dysfunction problem at chronic kidney insufficiency (the literature review)
Abstract
The article is devoted to the review of modern approaches to the development of endothelial dysfunction in chronic renal failure as on one of the main risk factors of disease progressing. The main links of the pathogenesis of the development of endothelial dysfunction are presented. Diagnostics questions of endothelial dysfunction and microcirculatory disturbance in patients with chronic renal failure are presented.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):55-58
55-58
Evolution of the treatment of chronic myeloid leukemia and dynamics correlation of quality of life in patients undergone the implementation in practice of tyrosine kinase inhibitors
Abstract
The article is devoted to review of current approaches to the pathogenesis, clinical course, diagnosis and evolution of the treatment of chronic myeloid leukemia from preparations of arsenic to tyrosine kinase inhibitors. In this article the modern concept of quality of life and types of questionnaires which are used to study quality of life in cancer patients has been described. The possibility of achieving a good health-related quality of life in patients with chronic myeloid leukemia after the implementation in practice of tyrosine kinase inhibitors has been considered.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):59-64
59-64
The role of endothelial state in patients with chronic renal failure undergoing programmed hemodialysis
Abstract
This article is devoted to review of current approaches to the development of endothelial dysfunction to the cardiovascular disease in patients with chronic renal failure undergoing programmed hemodialysis, as one of the main pathogenetic factors of disease progression. The influence of hemodialysis on endothelial function and different investigation methods of microcirculation disorders and endothelial dysfunction in patients with chronic renal failure undergoing programmed hemodialysis are shown.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):65-67
65-67
Clinical, diagnostic and prognostic value of cytogenetic and immunological impairments at chronic lymphoblastic
Abstract
Chronic lymphatic leukemia (CLL), the most common type of leukemia so the clinical picture and especially its course have been well investigated. At the same time, the lack of the necessary methodological approaches within long years didn't allow to make attempt to decipher the biological nature of the disease. The emergence of the modern cytogenetic, immunological and molecular methods has caused an explosion of interest in the study of CLL, and now the greatest amount of research in the field of Hematology is dedicated to the disease.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):68-70
68-70
The use of Artrocare in the treatment of patients with secondary osteoarthritis in rheumatoid arthritis on the basis therapy
Abstract
It the article the therapeutic approaches to the therapy of patients with secondary osteoarthritis in rheumatoid arthritis with the use of drug Artrocare (inhibitor of interleukin-1) on the basis therapy were shown. The efficacy of treatment with the use of indexes WOMAC, Lequesne, VAS, ESR, CRP and also cytokines IL-1,6, TNF-α was estimated. The analysis of the results revealed advantages of the use of drug Artrocare in comparison with the traditional therapy.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):71-73
71-73
Dynamics of full recovery of swallowing function in patients with acute ischemic stroke undergone neuromuscular electrical stimulation
Abstract
Dysphagia in acute stroke occurs in 20-90% of patients. The results of the examination and treatment of 112 patients with acute ischemic stroke are presented. The main group (group I, n = 55) received standard therapy of dysphagia and the patients of comparison group (group II, n = 57) - sessions of neuromuscular electrical stimulation. Full recovery (total score on a scale of FOIS ≥ 6) observed in 22 (38.5%) patients in Group I and only in 9 (16.3%) in group II (χ2 Yates correction = 5.85, p = 0.0156). After the treatment only 2 patients (3.5%) of group I had a nasogastric tubes and 10 patients in group II (18,2%) (χ2 Yates correction = 4.86, p = 0.0275). Aspiration pneumonia occurred in 3 (5.3%) patients in group I and in 11 (20.0%) patients in group II (χ2 Yates correction = 4.29, p = 0.0383). The factors of a poor prognosis for recovery of swallowing function were detected. A statistically significant correlation between the duration of submental muscle contraction group and on a scale MASA (r = -0,63, p <0,05) was revealed.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):74-78
74-78
Hysterosalpingography and hysteroscopy efficiency while the identification of intrauterine pathology at the stage of preparation for IVF
Abstract
In the article the results of comparative research of sensitivity and specificity hysterosalpingography and histeroscopy as revealing methods intrauterine pathology in the patients preparing to in vitro fertilisation, and also in fertility patients are presented. It is shown, that for inspection of a cavity of a uterus of the women preparing for IVF, it is more preferable to use histeroscopy since it possesses more sensitivity, than hysterosalpingography.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):79-81
79-81
Regional standards estimation and dynamics of the physical development of school children in Samara
Abstract
The author analyzes the indicators of the physical development of children (body weight, body length, body mass index) ranged from 6.5 to 16 years in age in Samara. Regional tables and maps to estimate the growth of the physical development of children ranged from 6.5 to 16 years in age are presented. A comparative analysis of the physical development of school children in the dynamics using the standards in 1998 is carried out. The features of the physical development of school children in Samara nowadays are revealed.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):82-85
82-85
The peculiarities of magnesium and hydroxyproline levels in pregnant women with symptoms of connective tissue dysplasia
Abstract
The paper presents the results of the analysis of magnesium and hydroxyproline levels of 500 pregnant women with symptoms of connective tissue dysplasia. Medical history data, the state of somatic profile are investigated, signs of connective tissue dysplasia are assessed according to T.Y.Smolnova et al (2003). The results show that the development of connective tissue dysplasia may be related to the destabilization of the system of exchange of magnesium and hydroxyproline.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):86-89
86-89
A complex method of the rehabilitation of reproductive function after ovarian surgery
Abstract
Ovarian apoplexy ranks second in intra-abdominal bleeding in women of reproductive age. With the introduction of new technologies in recent years the approach to diagnosis and treatment has changed, but the restoration of the reproductive function of women after ovarian surgery is unclear. The study demonstrates that a complex method of restoring reproductive function has the advantage with women patients in the traditional way.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):90-92
90-92
The complex assessment of clinical and laboratory findings in the women with endocrine infertility living in an ecologically unfavorable region
Abstract
N this work the characteristic of clinical, hormonal and immunological parameters in 114 patients with infertility caused by hypothyroidism and autoimmune thyroiditis living in anthropogenic pressure are presented. The data on the content of trace elements in the blood of women with infertility are shown.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):93-95
93-95
Preeclampsia Doppler markers as manifestation of intra-abdominal pressure and cardiovascular maladaptation
Abstract
The article focuses on pathogenetic and clinic significance of intra-abdominal pressure and cardiovascular maladaptation in cases of preeclampsia. This research illustrates the methods of predicting and early diagnosing of preeclampsia showing IAP and cardiovascular maladaptation proved by Doppler studies of renal and hepatic veins during pregnancy. Moreover, the article reviews literary sources on this problem and gives the author’s analysis of renal and hepatic Doppler data as well as estimation of diagnostic markers of IAP leading to preeclampsia.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):96-101
96-101
Efficiency estimation of partial pressure of oxygen in venous blood in the process of gestation treatment in the second trimester of pregnancy
Abstract
The level of partial pressure of oxygen in venous blood of 25 women with uncomplicated gestation and 70 patients with pregnancy complicated by preeclampsia, in the process of treatment of this complication of gestation in the second trimester of pregnancy was investigated. In the treatment of preeclampsia in 46 pregnant women from the main group the decline of the partial pressure of oxygen in the venous blood was noted, it was accompanied by a decrease in symptoms of this complication and prolongation of gestation, and 24 women from the main group there was an increase in the partial pressure of oxygen in the venous blood, and the severity of preeclampsia grew, followed by early abdominal delivery caused by the lack of proper treatment effect on pregnancy complications.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):102-104
102-104
The importance of heterosexual coitus as the way of AIDS transfer in the Samara region
Abstract
In this article the AIDS infection registered disease statistical data in the Samara region and ways of its transfer, and also quantity of children, which are born by AIDS-infected mothers are cited. More importance of heterosexual coitus is shown as the way of AIDS transfer. Negative short-term forecast of AIDS-infection vertical transmission in region is proved.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):105-107
105-107
The influence of latent iron deficiency in women with infertility on the pregnancy frequency in the IVF programs
Abstract
This prospective study evaluated 125 women, commencing IVF. All women were screened for latent iron deficiency. Depending on the results of the survey, the women were divided into two groups - with and without latent iron deficiency. The clinical pregnancy rate (17% versus 32%) was significantly lower in women with latent iron deficiency. This paper suggests that a common condition known as latent iron deficiency is associated with a reduced success following fertility treatment such as IVF.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):108-111
108-111
Catatrauma as a cause of pelvic injury
Abstract
WThe treatment of the patients with pelvic injuries caused by falls from a height during the period from 2001 to 2009 in the Arkhangelsk region was analyzed. Isolated, multiple and combined pelvic ring injuries were registered. The estimation of conservative and surgical treatment of the victims was made.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):112-115
112-115
Treatment result dynamics in patients with hernias depending on an operation way
Abstract
The assessment of the plastics in patients with postoperative ventral hernias (PVG) is of great practical importance. The purpose of the study is to analyse and evaluate the dynamics of the historical aspect of the treatment results of the patients with hernias in the transition from tension to non-pull way of close abdominal wall defects. Ways of operating applied in patients with hernias, for the time period were significantly different. Until 1998, the foundation of the constituent tension by means of plastic suggested by Mayo, Sapezhko and local fabrics were basic. Non-pull combined methods of hernia repair with the use of synthetic grafts, sewn on the first and second embodiments, have been introduced since 1998. The change in the treatment approach to the patients with PVG reduced the number of the lack of operation possibility for the sick persons, for technical reasons, regardless of their size from 24.5% to 8.4%, and the complications arising in the postoperative period in 2.7% of patients with large hernias and giant sizes were comparable to those in patients with hernia of small size. Plastic of hernial ring by local tissues was believed to be possible only in patients with hernia of small size, regardless of their location.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):116-119
116-119
A new way of getting the bone tumors biopsy
Abstract
In the course of the experiments of in-vitro the biopsy of bone tumors device (the patent of the Russian Federation № 109395, 2011) was developed. The purpose of the device creation is to get non-deformed column of biopsy material without damaging the layers of layers differentiation of in-vivo fabrics that increases reliability of the morphological diagnosis. On the basis of the office of the general oncology of the Samara Regional Clinical Oncological Clinic 42 biopsies were carried out by this developed way. Diagnostic accuracy of the clinical diagnosis making was 97,6%.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):120-123
120-123
124-126
Cytotoxic treatment complications in the patients with lung cancer
Abstract
Lung cancer - the leading cause of cancer mortality in most developed countries. Despite of the extensive development of the prevention, diagnosis and treatment, lung cancer has the highest incidence of all cancers among men and is the consistent upward trend in the incidence among women. Chemotherapy is one of the main methods of the treatment required for the most patients with lung cancer. A side effect of cytotoxic drugs is often limited. For the majority of side effects of anticancer agents corresponding grade 3 toxicity, and more, is an indication to stop chemotherapy and requires intensive treatment cover. Resuming chemotherapy depends on the completeness and rate of elimination of side effects and complications, which in turn, worsens the prognosis.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):127-130
127-130
Interrelation of morphological and functional state of renal scintigraphy in patients with kidney transplantation during post-transplantation period
Abstract
The author discussed questions of radionuclide study of morphological and functional state of kidney transplantation to the patient. Diagnostic opportunities of renal scintigraphy for such cases haven’t been fully investigated yet. This particular study determined the effect of focal lesions of the parenchyma kidney transplantation on the functional state of renal allograft using scintigraphy dynamic. Scintigram data handling and interpreting are presented by the author’s best knowledge. The obtained results show great diagnostic value of renal scintigraphy.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):131-133
131-133
Terms of restoration of the regional blood flow after successful vascular reconstruction in patients with lower limb ischaemia
Abstract
Terms of restoration of the regional blood flow after successful vascular reconstruction of 128 patients with lower limb ischaemia and necrosis of the distal portions of the foot were assessed. The ankle brachial index was revealed to be maximum to the end of 10th days at 76,5% cases after lower limb revascularization. Thus, any aggression on tissues of the distal portions of lower limbs performed before this time does not seem to be appropriate and can be even dangerous.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):134-136
134-136
Surgical treatment of proximal femoral fractures
Abstract
In the article our experience of surgical treatment of patients with proximal part of femur fracture with application of modern clamps is presented. The review of design features of modern metalclamps is given. The advantages and shortcomings at proximal part of femur osteosynthesis are described.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):137-139
137-139
Medical and social aspects of orthopedic dental treatment volume to over working age people (by example of the Samara regional dental policlinic)
Abstract
The article presents analysis results of orthopedic dental treatment volume to people over working age (by example of the Samara regional dental policlinic). It is established, that growth of total number of pensionable age people who received dentures was achieved by increasing orthopedic dental treatment to elderly citizens for a fee. The quantity of pensioners who can benefit accessible free prosthetic dental treatment from the budget is reduced.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):140-142
140-142
Diagnostics and treatment of patients with disk dislocation of a temporomandibular joint
Abstract
Dislocation of intra joint disk of a temporomandibular joint represents disk shift from a surface of a joint head and its jamming between elements of a temporomandibular joint. Research objective is to increase quality of diagnostics and treatment of patients with dislocation of disk of a temporomandibular joint by a choice of volume of diagnostic and medical actions. Object of research includes 52 patients with dislocation of disk of a temporomandibular joint. All patients surveyed according to the scheme including subjective, objective and express methods. The further complex treatment is undergone. In the end of the treatment which has been carried out according to the scheme, the normalization of the joint elements relationship is observed.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):143-147
143-147
Refraction features in patients with open-angle glaucoma
Abstract
We examined 110 patients with open-angle glaucoma in total 214 eyes. All the patients with an average age of 58.3 underwent refractometry to objectively determine the presence and degree of astigmatism. The degree of astigmatism was found to be more or equal to 0,5 D in 73% (158 eyes), with more or equal to 1.5 D in 17% (36 eyes). The prevalence of astigmatism in the patients with impaired hydrodynamics was revealed to be higher than in the general population. Astigmatism more than or equal 0.5D was accordingly observed almost 2 times more, and astigmatism more than or equal to 1.5 D was almost 4 times. By taking into consideration the association of optical, accommodative and simulation systems we can assume that the astigmatism can be one of the factors in the pathogenesis of open-angle glaucoma.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):148-150
148-150
Screening results and the treatment methods of diabetic retinopathy performed in diagnostic unit and ophthalmologic-endocrinology one
Abstract
It is known that the prevalence of the main complications of diabetes is 20 - 50% higher than the registered. For receiving reliable indicators, screening researches shouldn’t rely on traditional approaches and have local character. Medical and diagnostic opportunities of the only Russian mobile ophthalmologic medical and diagnostic module and ophthalmologic-endocrinology unit of GBUZ SRCOH of T.I. Eroshevsky as the tool for the solution of this problem are shown.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):151-155
151-155
Comparative assessment of hypotensive non-penetrating open-angle glaucoma surgery results
Abstract
The follow-ups of non-penetrating glaucoma surgery with collagen implant, that activates uveoscleral outflow, demonstrate its efficacy, safety. The activation of uveoscleral outflow shows considerable promise in glaucoma surgery. Ciliary muscle is the significant part of uveoscleral outflow pathway. It provides the active fluid flow. Therefore age and accommodation status are the important criteria of indications for surgery.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):156-159
156-159
The follow-ups of intracapsule cataract extraction in patients with subluxation crystalline lens
Abstract
The follow-ups of a new method of an intracapsule extraction of subluxation crystalline lens are investigated. The new technology doesn't provide the use of additional tools, a big corneal cut and is directed on preservation of a vitreous body membrane that allows to reduce considerably risk of cataract surgery complications. High-grade correction of an aphakia is used.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):160-163
160-163
Phaco-emulsification hypotensive effect depending on optical aberrations
Abstract
Detection of postoperative astigmatism due to the level of the hypotensive effect is examined. The maximum reduction in intraocular pressure is revealed to occur with astigmatism from 0 to 0.5 dioptre, the minimum - from 1.5-2.0.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):164-166
164-166
The relationship of the organ of vision and musculoskeletal systems of children with strabismus
Abstract
The work presents the relationship of the organ of vision and musculoskeletal systems of children with strabismus, as well as the treatment of amblyopia and the difference in visual acuity right and left eyes, including ophthalmologic methods with simultaneous stimulation of the bone-muscular system in order to restore their functional symmetry.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):167-169
167-169
Two-stage surgery treatment of patients with macular holes and cataracts
Abstract
In the article features and results of the surgical treatment of patients with macular holes and cataracts with the application of two-step surgery are studied. The first stage, phacoemulsification with IOL implantation was performed to all the patients. The second stage, microinvasive 25+ Gauge chromovitrectomy with application of endovitreal dye «Brilliant Blue G» on deuterium water was performed. Such a two-step concept allows the doctors to achieve high anatomic and functional results in treatment of macular holes and cataract in the early and follow up period of supervision. Intraoperative and postoperative complications are studied with anatomic and functional results.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):170-173
170-173
The cost of hospital admissions for the diabetes mellitus type 2 in the Volgograd region for 2006-2011
Abstract
The article presents the analysis of the frequency and cost of hospital admissions for the diabetes mellitus type 2 in the Volgograd region for 2006-2011. The calculations of the indicators of the average cost per admission and the number of hospitalized persons with type 2 diabetes for 1000 patients with this pathology are shown.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):174-176
174-176
Monitoring system of dugs and psychotropic preparations use
Abstract
The analysis of the legislative base in the field of traffic of narcotic drugs and psychotropic substances was performed. The structural analysis of the range of controlled substance groups and analysis of the violations related to narcotic drugs and psychotropic substances at medical institutions were carried out.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):177-179
177-179
Features of immunological profile of smoking patients with bronchial asthma
Abstract
This review represents contemporary scientific knowledge about immunological profile of smoking patients with bronchial asthma, the key points of influence of smoking on the immunological indicators of patients’ blood. The author pays great attention to the influence of smoking on the indicators of cytokine profile (IL-10, IL-17) and vascular endothelial growth factor (VEGF).
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):180-182
180-182
Concentration of protein S100B in patients with fat embolism syndrom
Abstract
Fat embolism syndrome (FES), a complication associated with fractures of long tubular bones or pelvis bones, is discussed. Classically, the clinical picture of FES develops after the «light interval» and followed by lung and neurological symptoms in combination with pin point bleeding. The diagnosis of FES is usually made on the base of clinical symptoms, and the set of large and small diagnostic criteria described by A.R. Gurd (1970) is used. Laboratory and instrumental techniques are used as well to confirm the clinical diagnosis or to monitor the therapy. In present study, we investigate a concentration of protein S100B in blood serum of the patients with acute trauma. An increase in the concentration of S100B is noted in patients with FES already in the first day of the post-traumatic period. The obtained data indicate a correlation between the concentration of S100B protein in blood serum and the severity of central nervous system defeat associated with FES.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):183-188
183-188
Diuretics influence on excretory kidney function experienced by artificial gravity and in normal stat
Abstract
Search of the new medicines possessing diuretic action, is an important problem of pharmacology. Diuretics promote removal from an organism of an excessive amount of water, salts, products of a proteinaceous exchange and the other substances unnecessary for an organism. In this regard these preparations are widely applied in all branches of medicine.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):189-191
189-191
Endothelium dysfunction at an experimental electrotrauma
Abstract
Some indicators of endothelium dysfunction at 20 laboratory rats under experiment with electrotrauma were investigated. By means of a simulated device the immobilized animals under anesthetic were run the risk of a dosed nonlethal electrotrauma with current tension of 220 V, current frequency of 50 Hz within 2 seconds. It was stated, that at electrotrauma the number of desquamative endotheliocytes increased, the production of nitric oxide decreased. Thus, the influence of current caused evident violations in endothelium function.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):192-194
192-194
Allergic pathology features in common disease aspect of adults in the Samara region
Abstract
The patient with allergic disease must be observed by doctors of primary health care services and particular specialists. A wide range of doctors, including primary care physicians should be familiar with the basic methods of evaluation of patients with allergic disease. The measures, which can lead to the improvement of compliance in the treatment can include: raising the awareness of patients of allergic diseases, conducting standardized epidemiological studies in the dynamics of the unified approaches to the diagnosis and treatment of allergic diseases. It is an actual study of quality of life parameters for further assessment of the physical, emotional, social status of the patient with allergic pathology, as well as the effectiveness of pharmacotherapy. It is necessary to introduce special questionnaires, taking into account, recommended by the WHO, the criteria of the quality of life and their components.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):195-201
195-201
Complex use perspectives of Camelina silvestris L
Abstract
The optimum extraction conditions of Camelina silvestris L. seeds were studied. The method of quantitative determination of flavonoids in the Camelina silvestris L. seeds was developed. For the first time from the Camelina silvestris L. seeds there was isolated 3-O-rutinoside of the isorhamnetin (narcissin). By having used of gas сhromatography there was studied fatty acid composition of fatty oil of Camelina silvestris L. seeds, cultivated in the Samara region. The dominant fatty acids, namely linolenic (30.7%), linoleic (20.6%), oleinic acid (17.6%) were identified. For the first time in the fatty oil of Camelina silvestris L. seeds there were found eicosadienic, docosadienic and selaсhoevic acids.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):202-204
202-204
Morphologic diagnostics of prostate ductal adenocarcinoma
Abstract
The morphologic features of tumors in patients with locally confined or advanced prostate ductal adenocarcinoma who had undergone radical prostatectomy were evaluated. Volumes of prostate gland, volumes of tumors, Gleason scores, pathologic stages, PSA levels were examined. We identified patients who had histologically pure ductal adenocarcinoma (18%), predominantly ductal adenocarcinoma (32%), whereas the other 50% had mixed ductal and acinar prostate cancer. 15 patients of the mixed pathology group also had evidence of neuroendocrine, sarcomatoid, mucinus or squamous differentiation. Differential diagnosis must exclude high grade prostatic intraepithelial neoplasia, non-ductal intraductal adenocarcinoma, cribriform acinar adenocarcinoma.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):205-209
205-209
Optimization of the temperature conditions for drying bilberry fruits
Abstract
With the using of thin-layer chromatography and spectrophotometry the conditions for drying bilberry fruits there were defined that minimize the loss of anthocyanins as the most labile group of biologically active compounds of the plant material. The fruits should have been dried at temperature range +40-50 °C at a layer thickness of 2 cm to attain a residual humidity of 17%.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):210-212
210-212
Multiple instability of atherosclerotic plaques of non-coronal location in patients with acute coronary syndrome
Abstract
An unstable atherosclerotic plaque is resulted from the activation of endogenous intravascular inflammation, which is systematically. The study of morphogenesis of atherosclerosis in peripheral arteries in the presence of unstable plaques in the coronary artery can specify new therapeutic targets for the prevention of repeated acute vascular events. The paper shows the existence of unstable and complicated plaques in patients with acute coronary syndrome both in clinically significant peripheral atherosclerosis and in the latent period of these diseases.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):213-218
213-218
The investigation of composition and physical-chemical constants of fatty oil of Carthamus tinctorius L. seed’s
Abstract
By having used of the method of a gas chromatography there was studied the composition of fatty oil of Carthamus tinctorius L. seed’s cultivated in the Samara region. In the content of seed oil of this plant there were determined 10 fatty acids. The main fatty acid of the Carthamus tinctorius L. seed oils is linoleic acid (78,5%) was shown. By having used of spectrophotometry there was determined in the Carthamus tinctorius L. seed oils the content of total carotenoids which was 1,40 ± 0,02 mg%. Basic physical-chemical constants for Carthamus tinctorius L. seed oils were studied.
Aspirantskiy Vestnik Povolzhiya. 2013;13(1-2):219-222
219-222