Nursing profoundly premature newborns with artificial placentae: a review

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Abstract

Neonatal mortality and morbidity are substantial issues affecting the maternal healthcare sector. Extremely premature infants, notably those born before the 28-week mark, experience significant morbidity and mortality rates during neonatal care. This is a result of developmental immaturity and iatrogenic injury. Several attempts have been made to develop a womb-like environment to mimic uteroplacental physiology, but limited success has been noted over the last decade. This review aims to summarize the current literature on improved techniques implemented in creating an artificial placenta, the principles of these procedures, and their limitations. Our findings indicate that implementing techniques that closely mimic uteroplacental pathophysiology is crucial in decreasing the excessive neonatal mortality and morbidity rates seen in extremely premature infants.

About the authors

Akinyemi Oyedele

I.M. Sechenov First Moscow State Medical University

Email: akinyo11@gmail.com
ORCID iD: 0000-0001-7429-6834

MD, resident of the 2nd year of study

Russian Federation, 119991, Moscow

Morakinyo Oyedele

I.M. Sechenov First Moscow State Medical University

Email: morakinyo.oyedele@hotmail.com
ORCID iD: 0000-0002-2093-4754

MD, resident of the 2nd year of study

Russian Federation, 119991, Moscow

Andrey V. Murashko

I.M. Sechenov First Moscow State Medical University

Author for correspondence.
Email: murashkoa@mail.ru
ORCID iD: 0000-0003-0663-2909
SPIN-code: 2841-9638

M.D., Dr. Sci. (Med.), professor

Russian Federation, 119991, Moscow

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