The role of circadian rhythms and the “cellular clock” in age-associated diseases


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Circadian oscillations are characteristic of almost all processes in living organisms. Disturbances in circadian rhythms may constitute either a cause or a consequence of different diseases. The article analyzes literature data on the role of changes in the circadian rhythms and the expression of clock genes in the development of neurodegenerative and cardiovascular diseases, metabolic syndrome, and type 2 diabetes mellitus in human beings and animals.

Sobre autores

A. Panchenko

Petrov Research Institute of Oncology; Almazov Northwestern Federal Medical Research Center

Autor responsável pela correspondência
Email: ando_pan@mail.ru
Rússia, pos. Pesochnyi, St. Petersburg, 197758; St. Petersburg, 197341

E. Gubareva

Petrov Research Institute of Oncology

Email: ando_pan@mail.ru
Rússia, pos. Pesochnyi, St. Petersburg, 197758

V. Anisimov

Petrov Research Institute of Oncology

Email: ando_pan@mail.ru
Rússia, pos. Pesochnyi, St. Petersburg, 197758

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