Comparative organometric characteristic of the cerebellum of the young and old age

Abstract

This scientific work is based on morphological research of the cerebellums of 219 corpses of people (108 men and 111 women) of young and senile age. Organometric, histological, and morphometric methods were used. During the study, a comparative analysis of the mass, linear dimensions, and thickness of the cerebral cortex in young and senile age was conducted. The regularities of age variability of organometric characteristic of the cerebellum were revealed, and they were found in the reduction of mass and linear dimensions of the cerebellum in people of senile age compared to younger people. It was determined that the thickness of the molecular and granular layers of the cerebellum was characterized by age-related decrease of the parameters. The results of the morphological study can serve as a basis for the identification of certain regularities of age anatomy of the cerebellum and have practical significance as indicators of the norm that allows using these data in diagnostic and therapeutic work.