Comparative analysis of different geroprotective methods


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Abstract

One hundred and ten patients of different ages have undergone a comparative analysis of the efficiency and safety of a number of geroprotective techniques, including the use of dry lead-carbonate baths, hyperbaric oxygenation, therapeutic massage, and reception of oligopeptide preparations containing complexes of lysyl-glutamyl-asparagin and glutamyl-asparagin-arginine complexes (Vezugen and Pinealon). The most pronounced positive impact on indicators of biological age was found during the combined use of these two oligopeptide complexes. The safest ones in terms of influence on a number of biochemical and immunological parameters and on the clinical state of patients were medical massage and oligopeptide preparations. The use of dry carbon dioxide baths and hyperbaric oxygenation, while having an undoubtedly positive influence on the indices of biological age, has a number of limitations and counterindications.

About the authors

V. S. Myakotnykh

Ural State Medical University

Author for correspondence.
Email: vmaykotnykh@yandex.ru
Russian Federation, Yekaterinburg

M. N. Torgashov

Ural State Medical University

Email: vmaykotnykh@yandex.ru
Russian Federation, Yekaterinburg

K. V. Egorin

Ural State Medical University

Email: vmaykotnykh@yandex.ru
Russian Federation, Yekaterinburg

V. N. Meshchaninov

Ural State Medical University; Institute of Medical Cell Technologies

Email: vmaykotnykh@yandex.ru
Russian Federation, Yekaterinburg; Yekaterinburg

I. V. Gavrilov

Ural State Medical University; Institute of Medical Cell Technologies

Email: vmaykotnykh@yandex.ru
Russian Federation, Yekaterinburg; Yekaterinburg

T. A. Borovkova

Ural State Medical University

Email: vmaykotnykh@yandex.ru
Russian Federation, Yekaterinburg

E. M. Zvezdina

Ural State Medical University

Email: vmaykotnykh@yandex.ru
Russian Federation, Yekaterinburg

T. Y. Verzhbitskaya

Institute of Medical Cell Technologies

Email: vmaykotnykh@yandex.ru
Russian Federation, Yekaterinburg

E. L. Tkachenko

Institute of Medical Cell Technologies

Email: vmaykotnykh@yandex.ru
Russian Federation, Yekaterinburg


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