Investigation of physicochemical and biological properties of composite matrices in a alginate–calcium phosphate system intended for use in prototyping technologies during replacement of bone defects
- Authors: Komlev V.S.1, Sergeeva N.S.2, Fedotov A.Y.1, Sviridova I.K.2, Kirsanova V.A.2, Akhmedova S.A.2, Teterina A.Y.1, Zobkov Y.V.1, Kuvshinova E.A.2, Shanskiy Y.D.2, Barinov S.M.1
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Affiliations:
- Baikov Institute of Metallurgy and Materials Science
- Medical Radiological Research Centre of the Ministry of Health
- Issue: Vol 7, No 4 (2016)
- Pages: 630-634
- Section: Article
- URL: https://journals.rcsi.science/2075-1133/article/view/205602
- DOI: https://doi.org/10.1134/S2075113316040158
- ID: 205602
Cite item
Abstract
Materials for 3D printing of porous composite materials (CM) that are based on sodium alginate–tricalcium phosphate are developed. Physicochemical and biological studies of CM in vitro are performed using a model of two adherent cells lines, immortalized human fibroblasts (HF, strain 1608h TERT) and human osteosarcoma (MG-63) that are cultivated up to 21 days. The cytocompatibility and matrix properties are studied by an MTT assay.
About the authors
V. S. Komlev
Baikov Institute of Metallurgy and Materials Science
Author for correspondence.
Email: komlev@mail.ru
Russian Federation, Moscow
N. S. Sergeeva
Medical Radiological Research Centre of the Ministry of Health
Email: komlev@mail.ru
Russian Federation, Obninsk
A. Yu. Fedotov
Baikov Institute of Metallurgy and Materials Science
Email: komlev@mail.ru
Russian Federation, Moscow
I. K. Sviridova
Medical Radiological Research Centre of the Ministry of Health
Email: komlev@mail.ru
Russian Federation, Obninsk
V. A. Kirsanova
Medical Radiological Research Centre of the Ministry of Health
Email: komlev@mail.ru
Russian Federation, Obninsk
S. A. Akhmedova
Medical Radiological Research Centre of the Ministry of Health
Email: komlev@mail.ru
Russian Federation, Obninsk
A. Yu. Teterina
Baikov Institute of Metallurgy and Materials Science
Email: komlev@mail.ru
Russian Federation, Moscow
Yu. V. Zobkov
Baikov Institute of Metallurgy and Materials Science
Email: komlev@mail.ru
Russian Federation, Moscow
E. A. Kuvshinova
Medical Radiological Research Centre of the Ministry of Health
Email: komlev@mail.ru
Russian Federation, Obninsk
Ya. D. Shanskiy
Medical Radiological Research Centre of the Ministry of Health
Email: komlev@mail.ru
Russian Federation, Obninsk
S. M. Barinov
Baikov Institute of Metallurgy and Materials Science
Email: komlev@mail.ru
Russian Federation, Moscow