Investigation of physicochemical and biological properties of composite matrices in a alginate–calcium phosphate system intended for use in prototyping technologies during replacement of bone defects

V. S. Komlev; N. S. Sergeeva; A. Yu. Fedotov; I. K. Sviridova; V. A. Kirsanova; S. A. Akhmedova; A. Yu. Teterina; Yu. V. Zobkov; E. A. Kuvshinova; Ya. D. Shanskiy; S. M. Barinov

doi:10.1134/S2075113316040158

Investigation of physicochemical and biological properties of composite matrices in a alginate–calcium phosphate system intended for use in prototyping technologies during replacement of bone defects

Autores: Komlev V.¹, Sergeeva N.², Fedotov A.¹, Sviridova I.², Kirsanova V.², Akhmedova S.², Teterina A.¹, Zobkov Y.¹, Kuvshinova E.², Shanskiy Y.², Barinov S.¹
Afiliações:
1. Baikov Institute of Metallurgy and Materials Science
2. Medical Radiological Research Centre of the Ministry of Health
Edição: Volume 7, Nº 4 (2016)
Páginas: 630-634
Seção: Article
URL: https://journals.rcsi.science/2075-1133/article/view/205602
DOI: https://doi.org/10.1134/S2075113316040158
ID: 205602

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Materials for 3D printing of porous composite materials (CM) that are based on sodium alginate–tricalcium phosphate are developed. Physicochemical and biological studies of CM in vitro are performed using a model of two adherent cells lines, immortalized human fibroblasts (HF, strain 1608h TERT) and human osteosarcoma (MG-63) that are cultivated up to 21 days. The cytocompatibility and matrix properties are studied by an MTT assay.