Investigation of physicochemical and biological properties of composite matrices in a alginate–calcium phosphate system intended for use in prototyping technologies during replacement of bone defects


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Materials for 3D printing of porous composite materials (CM) that are based on sodium alginate–tricalcium phosphate are developed. Physicochemical and biological studies of CM in vitro are performed using a model of two adherent cells lines, immortalized human fibroblasts (HF, strain 1608h TERT) and human osteosarcoma (MG-63) that are cultivated up to 21 days. The cytocompatibility and matrix properties are studied by an MTT assay.

作者简介

V. Komlev

Baikov Institute of Metallurgy and Materials Science

编辑信件的主要联系方式.
Email: komlev@mail.ru
俄罗斯联邦, Moscow

N. Sergeeva

Medical Radiological Research Centre of the Ministry of Health

Email: komlev@mail.ru
俄罗斯联邦, Obninsk

A. Fedotov

Baikov Institute of Metallurgy and Materials Science

Email: komlev@mail.ru
俄罗斯联邦, Moscow

I. Sviridova

Medical Radiological Research Centre of the Ministry of Health

Email: komlev@mail.ru
俄罗斯联邦, Obninsk

V. Kirsanova

Medical Radiological Research Centre of the Ministry of Health

Email: komlev@mail.ru
俄罗斯联邦, Obninsk

S. Akhmedova

Medical Radiological Research Centre of the Ministry of Health

Email: komlev@mail.ru
俄罗斯联邦, Obninsk

A. Teterina

Baikov Institute of Metallurgy and Materials Science

Email: komlev@mail.ru
俄罗斯联邦, Moscow

Yu. Zobkov

Baikov Institute of Metallurgy and Materials Science

Email: komlev@mail.ru
俄罗斯联邦, Moscow

E. Kuvshinova

Medical Radiological Research Centre of the Ministry of Health

Email: komlev@mail.ru
俄罗斯联邦, Obninsk

Ya. Shanskiy

Medical Radiological Research Centre of the Ministry of Health

Email: komlev@mail.ru
俄罗斯联邦, Obninsk

S. Barinov

Baikov Institute of Metallurgy and Materials Science

Email: komlev@mail.ru
俄罗斯联邦, Moscow

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