Continuous epidural block in complex intensive therapy of severe acute pancreatitis


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Abstract

The prospective study included 220 patients with severe acute pancreatitis. From this group 105 individuals received continuous epidural blockade (EB) with 0.2% ropivacain solution for 3-7 days. The rest of patients were enrolled into control group. Continuous EB promoted the decrease of intra-abdomenal pressure and allowed introducing the enteral nutrition 2-3 days earlier. Patients from EB group have less lung complications comparing with control group. Total incidence of purulent intra-abdomenal complications was 20,0% in EB group while in control group - 51,3%. The EB conducting contributed into decrease of period of staying in intensive care unit and in hospital as a whole. The incidence of mortality was 11,4% in EB group while in control group it was 15,6%. We concluded that performing of continuous epidural block at early stage of severe acute pancreatitis as an intensive therapy component results in decreasing of frequency of life-threatening complications and mortality.

About the authors

Valeriy V. Frolkov

SBIH City clinical hospital #23 “MedSanTrud”

Email: frolkov@rambler.ru
109240, Moscow

M. Ya Krasnosel’skiy

SBEI “I.M. Sechenov First Moscow State Medical University” of MHC of RF

119991, Moscow

A. M Ovechkin

SBEI “I.M. Sechenov First Moscow State Medical University” of MHC of RF

119991, Moscow

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