Email this article THE SPECIFIC FEATURES OF FLUORESCEIN ANGIOGRAPHY OF THE RETINA IN THE CHILDREN OF DIFFERENT AGE AND THE POSSIBLE COMPLICATIONS OF ITS APPLICATION
- Authors: Zaitcev N.A.1
-
Affiliations:
- Federal state budgetary educational institution of higher education “Saint-Petersburg State Pediatric Medical University”, Russian Ministry of Health
- Issue: Vol 12, No 2 (2017)
- Pages: 82-86
- Section: Articles
- URL: https://journals.rcsi.science/1993-1859/article/view/39537
- DOI: https://doi.org/10.18821/1993-1859-2017-12-2-82-86
- ID: 39537
Cite item
Full Text
Abstract
Purpose. The objective of the present study was the further adaptation of the fluorescence angiography technique for the examination of the children of different ages and the evaluation of the nature, severity, and frequency of complications likely to develop in the course of such examination as a result of intravenous administration of sodium fluorescein and its intake. Material and methods. A total of 957 children at the age varying between 1.5 months and 16 years were divided into two age groups. The first group consisted of 204 (21.3%) children under the age of 1.5 months and up to 5 years including premature babies in whom fluorescence retinal angiography was performed under general anesthesia with the use of the specially developed and improved methodology. The second group was comprised of 753 (78.7%) children at the age between 6 and 16 years. To 649 of these children (86.2%), the dye was injected intravenously whereas to 104 (13.8%) of them sodium fluorescein was given per os. Results. We have developed and further improved the method for fluorescence angiography in the children of various ages including premature infants. The fluorescence angiography of the fundus of the eye in the children at the age from 1.5 months and up to 16 years resulted in the complications of varying severity in 5.2% of the patients. Mild complications in the form of nausea or vomiting accounted for 3.8% of their total number. The moderately severe complications (1.0%) manifested themselves as the development of the collaptoid state or urticaria. The severe complications (0.2%) were apparent as bronchospasm and laryngospasm. No complications whatever were documented in the children after the oral intake of a 10% sodium fluorescein solution. Conclusion. The intravenous fluorescence angiography is a fairly safe method for the examination of the fundus of the eye in the children, however it can be accompanied in rare cases (3.8%) by the complications the majority of which (75%) are mild disorders. Both intravenous administration of sodium fluorescein under general anesthesia and its oral intake can be regarded as safe interventions.
Full Text
##article.viewOnOriginalSite##About the authors
Nikolai Anatol’evich Zaitcev
Federal state budgetary educational institution of higher education “Saint-Petersburg State Pediatric Medical University”, Russian Ministry of Health
Email: zaitcev-doc@yandex.ru
assistant professor for the Department of Ophthalmology, Federal state budgetary educational institution of higher education “Saint-Petersburg State Pediatric Medical University”, Russian Ministry of Health, Saint-Petersburg, 194100, Russian Federation Saint-Petersburg, 194100, Russian Federation
References
- Butrus S.I., Negvesky G.J., Rivera-Velazques P.M. et al. Serum tryptase: an indicator of anaphylaxis following fluorescein angiography. Graefes Arch. Clin. Exp. Ophthalmol.1999; 237 (5): 433-4.
- Kwiterovich K.A., Maguire M.G., Murphy R.P. et al. Frequency of adverse systemic reactions after fluorescein angiography. Results of a prospective study. Ophthalmology.1991; 98 (7): 1139-42.
- Zografos L. International survey on the incidence of severe or fatal complications which may occur during fluorescein angiography. J. Fr. Ophtalmol. 1983; 6 (5): 495-506.
- Marcus D.F., Bovino J.A., Williams D. Adverse reactions during intravenous fluorescein angiography. Arch. Ophthalmol. 1984; 102 (6): 825.
- Johnson R.N., McDonald H.R., Schatz H. Rash, fever, and chills after intravenous fluorescein angiography. Am. J. Ophthalmol. 1998; 126 (6): 837-8.
- Trindade-Porto C., Alonso-Llamazares A., Robledo T. et al. Fluorescein- induced adverse reaction. Allergy. 1999; 54 (11): 1230.
- Ascaso F.J., Tiestos M.T., Navales J. et al. Fatal acute myocardial infarction after intravenous fluorescein angiography. Retina. 1993; 13 (3): 238-9.
- Fineschi V., Monasterolo G., Rosi R. et al. Fatal anaphylactic shok during a fluorescein angiography. Forensic Sci. Int. 1999; 100 (1): 137-42.
- Kinsella F.P., Mooney D.J. Anaphylaxis following oral fluorescein angiography. Am. J. Ophthalmol. 1988; 106 (6): 745-6.
- Зайцев Н.А. Флюоресцентная ангиография сетчатки у детей раннего возраста: В кн.: Избранные вопросы клинической офтальмологии. Сборник научных трудов кафедры офтальмологии СПбМАПО. СПб.; 1994: 11-2.
- Зайцев Н.А., Сомов Е.Е., Чутко С.М. Опыт применения флюоресцентной ангиографии сетчатки у детей раннего возраста. В кн.: Материалы VII Съезда офтальмологов. М.; 1994: 189-90.
- Зайцев Н.А., Сомов Е.Е., Чутко С.М. Объективизация результатов офтальмоскопии у недоношенных детей: В кн.: Материалы VII Съезда офтальмологов. М.; 1994: 190-1.
- Зайцев Н.А., Сомов Е.Е. Характер возможных осложнений при проведении флюоресцентной ангиографии у детей различного возраста. Офтальмологические ведомости. 2010; (3): 14-7.
- Зайцев Н.А. Флюоресцентная ангиография сетчатки у детей различного возраста. В кн.: Сомов Е.Е. (ред.). Избранные разделы детской клинической офтальмологии. СПб.: Человек; 2016: 208-17.
