Отправить статью по E-mail Structural Investigation of Biomacromolecules Using Ultrahigh-Resolution Mass Spectrometry and Isotope Exchange
- Авторы: Kostyukevich Y.I.1,2,3, Kononikhin A.S.2,3, Popov I.A.2,3, Nikolaev E.N.1,2,3
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Учреждения:
- Skolkovo Institute of Science and Technology
- Moscow Institute of Physics and Technology
- Tal’roze Institute for Energy Problems of Chemical Physics
- Выпуск: Том 12, № 4 (2018)
- Страницы: 599-604
- Раздел: XXIX Russian Symposium “Modern Chemical Physics” (Tuapse, Russia, September 2017)
- URL: https://journals.rcsi.science/1990-7931/article/view/200761
- DOI: https://doi.org/10.1134/S1990793118040243
- ID: 200761
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Аннотация
We present a new analysis methodology for arbitrary complex molecular systems using ultrahigh-resolution mass spectrometry and isotope exchange. The kinetics of the hydrogen–deuterium exchange reaction is described for large biomacromolecules. The possible applications of the proposed methodology for the analysis of linear oligosaccharides, proteins, and molecular ensemble of humic acids are discussed.
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Y. Kostyukevich
Skolkovo Institute of Science and Technology; Moscow Institute of Physics and Technology; Tal’roze Institute for Energy Problems of Chemical Physics
Автор, ответственный за переписку.
Email: y.kostyukevich@skoltech.ru
Россия, Skolkovo, 143025; Dolgoprudnyi, Moscow, 141700; Moscow, 119334
A. Kononikhin
Moscow Institute of Physics and Technology; Tal’roze Institute for Energy Problems of Chemical Physics
Email: y.kostyukevich@skoltech.ru
Россия, Dolgoprudnyi, Moscow, 141700; Moscow, 119334
I. Popov
Moscow Institute of Physics and Technology; Tal’roze Institute for Energy Problems of Chemical Physics
Email: y.kostyukevich@skoltech.ru
Россия, Dolgoprudnyi, Moscow, 141700; Moscow, 119334
E. Nikolaev
Skolkovo Institute of Science and Technology; Moscow Institute of Physics and Technology; Tal’roze Institute for Energy Problems of Chemical Physics
Email: y.kostyukevich@skoltech.ru
Россия, Skolkovo, 143025; Dolgoprudnyi, Moscow, 141700; Moscow, 119334
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