Enviar artigo por via de e-mail Structural Investigation of Biomacromolecules Using Ultrahigh-Resolution Mass Spectrometry and Isotope Exchange
- Autores: Kostyukevich Y.I.1,2,3, Kononikhin A.S.2,3, Popov I.A.2,3, Nikolaev E.N.1,2,3
-
Afiliações:
- Skolkovo Institute of Science and Technology
- Moscow Institute of Physics and Technology
- Tal’roze Institute for Energy Problems of Chemical Physics
- Edição: Volume 12, Nº 4 (2018)
- Páginas: 599-604
- Seção: XXIX Russian Symposium “Modern Chemical Physics” (Tuapse, Russia, September 2017)
- URL: https://journals.rcsi.science/1990-7931/article/view/200761
- DOI: https://doi.org/10.1134/S1990793118040243
- ID: 200761
Citar
Acesso aberto
Acesso está concedido
Somente assinantes
Resumo
We present a new analysis methodology for arbitrary complex molecular systems using ultrahigh-resolution mass spectrometry and isotope exchange. The kinetics of the hydrogen–deuterium exchange reaction is described for large biomacromolecules. The possible applications of the proposed methodology for the analysis of linear oligosaccharides, proteins, and molecular ensemble of humic acids are discussed.
Palavras-chave
Sobre autores
Y. Kostyukevich
Skolkovo Institute of Science and Technology; Moscow Institute of Physics and Technology; Tal’roze Institute for Energy Problems of Chemical Physics
Autor responsável pela correspondência
Email: y.kostyukevich@skoltech.ru
Rússia, Skolkovo, 143025; Dolgoprudnyi, Moscow, 141700; Moscow, 119334
A. Kononikhin
Moscow Institute of Physics and Technology; Tal’roze Institute for Energy Problems of Chemical Physics
Email: y.kostyukevich@skoltech.ru
Rússia, Dolgoprudnyi, Moscow, 141700; Moscow, 119334
I. Popov
Moscow Institute of Physics and Technology; Tal’roze Institute for Energy Problems of Chemical Physics
Email: y.kostyukevich@skoltech.ru
Rússia, Dolgoprudnyi, Moscow, 141700; Moscow, 119334
E. Nikolaev
Skolkovo Institute of Science and Technology; Moscow Institute of Physics and Technology; Tal’roze Institute for Energy Problems of Chemical Physics
Email: y.kostyukevich@skoltech.ru
Rússia, Skolkovo, 143025; Dolgoprudnyi, Moscow, 141700; Moscow, 119334
Arquivos suplementares
