电邮这篇文章 Structural Investigation of Biomacromolecules Using Ultrahigh-Resolution Mass Spectrometry and Isotope Exchange
- 作者: Kostyukevich Y.I.1,2,3, Kononikhin A.S.2,3, Popov I.A.2,3, Nikolaev E.N.1,2,3
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隶属关系:
- Skolkovo Institute of Science and Technology
- Moscow Institute of Physics and Technology
- Tal’roze Institute for Energy Problems of Chemical Physics
- 期: 卷 12, 编号 4 (2018)
- 页面: 599-604
- 栏目: XXIX Russian Symposium “Modern Chemical Physics” (Tuapse, Russia, September 2017)
- URL: https://journals.rcsi.science/1990-7931/article/view/200761
- DOI: https://doi.org/10.1134/S1990793118040243
- ID: 200761
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详细
We present a new analysis methodology for arbitrary complex molecular systems using ultrahigh-resolution mass spectrometry and isotope exchange. The kinetics of the hydrogen–deuterium exchange reaction is described for large biomacromolecules. The possible applications of the proposed methodology for the analysis of linear oligosaccharides, proteins, and molecular ensemble of humic acids are discussed.
作者简介
Y. Kostyukevich
Skolkovo Institute of Science and Technology; Moscow Institute of Physics and Technology; Tal’roze Institute for Energy Problems of Chemical Physics
编辑信件的主要联系方式.
Email: y.kostyukevich@skoltech.ru
俄罗斯联邦, Skolkovo, 143025; Dolgoprudnyi, Moscow, 141700; Moscow, 119334
A. Kononikhin
Moscow Institute of Physics and Technology; Tal’roze Institute for Energy Problems of Chemical Physics
Email: y.kostyukevich@skoltech.ru
俄罗斯联邦, Dolgoprudnyi, Moscow, 141700; Moscow, 119334
I. Popov
Moscow Institute of Physics and Technology; Tal’roze Institute for Energy Problems of Chemical Physics
Email: y.kostyukevich@skoltech.ru
俄罗斯联邦, Dolgoprudnyi, Moscow, 141700; Moscow, 119334
E. Nikolaev
Skolkovo Institute of Science and Technology; Moscow Institute of Physics and Technology; Tal’roze Institute for Energy Problems of Chemical Physics
Email: y.kostyukevich@skoltech.ru
俄罗斯联邦, Skolkovo, 143025; Dolgoprudnyi, Moscow, 141700; Moscow, 119334
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