Email this article THE MODERN METHODS FOR THE CORRECTION OF NON-NEOPLASTIC MELANIN HYPERPIGMENTATION OF THE SKIN AND THE INTEGRATED APPROACH TO THEIR TREATMENT
- Authors: Ikonnikova E.V1, Stenko A.G2, Korchazhkina N.B1
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Affiliations:
- Federal state budgetary institution of additional professional education «Central State Medical Academy», Presidential Administration of the President of Russian Federation
- Open joint-stock company «Institute of Plastic Surgery and Cosmetology»
- Issue: Vol 16, No 2 (2017)
- Pages: 84-88
- Section: Articles
- URL: https://journals.rcsi.science/1681-3456/article/view/41643
- DOI: https://doi.org/10.18821/1681-3456-2017-16-2-84-88
- ID: 41643
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Abstract
Skin hyperpigmentation is one of the most common conditions that attract the attention of both the dermatologists and the cosmetologists since the cosmetic defects associated with this pathology are known to greatly deteriorate the quality of life of the patients. This article presents information about the most popular modern methods for the correction of non-neoplastic melanin hyperpigmentation of the skin. The main trends in the application of the external agents, laser and light therapy as well as the possibility of the combination of some of these techniques are considered. Methods: A total of 24 patients presenting with various clinical forms of non-neoplastic melanin hyperpigmentation of the skin aged from 25 to 62 years were under supervision in the present study. The pathological process was mainly localized on the face, the neckline and the back of the hands in 21 (87.5%) patients, on the skin of the trunk and the extremities in 3 (12.5%) ones. All the patients received topical therapy with the use of the products containing glycolic acid and ascorbic acids in the form of both drug monotherapy and its combination with laser therapy (at a wavelength of 1064 nm). Results: The study has demonstrated that the topical application of the products containing glycolic acid and ascorbic acid as a monotherapy provides a highly efficacious and safe method for the aesthetic correction of skin hyperpigmentation. However, its combination with laser therapy (at a wavelength of 1064 nm) produces a significantly higher therapeutic effect as confirmed by the present study.
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##article.viewOnOriginalSite##About the authors
E. V Ikonnikova
Federal state budgetary institution of additional professional education «Central State Medical Academy», Presidential Administration of the President of Russian Federation
Author for correspondence.
Email: evikonnikova@bk.ru
ассистент кафедры дерматовенерологии и косметологии ФГБУ ДПО «Центральная государственная медицинская академия» Управления делами Президента РФ, 121359, Москва, Россия
121359, Moscow, Russian FederationA. G Stenko
Open joint-stock company «Institute of Plastic Surgery and Cosmetology»
Email: info@eco-vector.com
105066, Moscow, Russian Federation
N. B Korchazhkina
Federal state budgetary institution of additional professional education «Central State Medical Academy», Presidential Administration of the President of Russian Federation
Email: info@eco-vector.com
121359, Moscow, Russian Federation
References
- Потекаев Н.Н., Круглова Л.С. Гиперпигментация: причины возникновения и методы коррекции. Клиническая дерматология и венерология. 2012; 10 (6): 65-70.
- Круглова Л.С., Стенько А.Г., Стрелкович Т.И. Этиология, патогенез, классификация и современные возможности лечения неопухолевых гиперпигментаций кожи. Пластическая хирургия и косметология. 2014; (1): 105-10.
- Круглова Л.С., Котенко К.В., Корчажкина Н.Б., Турбовская С.Н. Физиотерапия в дерматологии. М.: ГЭОТАР; 2016.
- Потекаев Н.Н., Круглова Л.С. Лазер в дерматологии и косметологии. М.: МДВ; 2012.
- Бауманн Л. Косметическая дерматология: принципы и практика. М.: Медпресс-информ; 2012.
- Ibrahim Z.A., Gheida S.F., El Maghraby G.M., Farag Z.E. Evaluation of the efficacy and safety of combinations of hydroquinone, glycolic acid, and hyaluronic acid in the treatment of melasma. J. Cosmet. Dermatol. 2015; 14 (2): 113-23.
- Gilchrest B.A. A review of skin ageing and its medical therapy. Br. J. Dermatol. 1996; 135: 867-75.
- Vashi N.A., Kundu R.V. Facial hyperpigmentation: causes and treatment. Br. J. Dermatol. 2013; 169 (3): 41-56.
- Bang S.H., Han S.J., Kim D.H. Hydrolysis of arbutin to hydroquinone by human skin bacteria and its effect on antioxidant activity. J. Cosmet. Dermatol. 2008; 7 (3): 189-93.
- Chaudhary S., Dayal S. Efficacy of combination of glycolic acid peeling with topical regimen in treatment of melasma. J. Drugs. Dermatol. 2013; 12 (10): 1149-53.
- Cardinali G., Kovacs D., Picardo M. Mechanisms underlying post-inflammatory hyperpigmentation: lessons from solar lentigo. Ann. Dermatol. Venereol. 2012; 139(3): 96-101.
- Lee A.Y. Recent progress in melasma pathogenesis. Pigment Cell Melanoma Res. 2015; 28 (6): 648-60.
- Patil U.A., Dhami L.D. Overview of lasers. Ind. J. Plast. Surg. 2008; 41: 101-13.
- Park G.H., Rhee do Y., Moon H.R., Won C.H., Lee M.W., Choi J.H. et al. Effect of an epidermal growth factor-containing cream on postinflammatory hyperpigmentation after Qswitched 532-nm neodymium-doped yttrium aluminum garnet laser treatment. Dermatol. Surg. 2015; 41 (1): 131-5.
- Negishi K., Tanaka S., Tobita S. Prospective, randomized, evaluator-blinded study of the long pulse 532-nm KTP laser alone or in combination with the long pulse 1064-nm Nd: YAG laser on facial rejuvenation in Asian skin. Lasers Surg. Med. 2016; 48 (9): 844-51.
- Ryu H.J., Lee J.M., Jang H.W., Park H.C., Rhyu I.J., Kim I.H. Morphologic changes of zebrafish melanophore after intense pulsed light and Q-switched Nd:YAG laser irradiation. Ann. Dermatol. 2016; 28 (6): 711-7.
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