Effectiveness of digital and telemedicine technologies in the rehabilitation of patients with dorsopathies and chronic pain: a review
- Authors: Zakiev A.M.1, Yusupova A.R.1, Khalfieva D.M.1, Khuzina V.R.1, Kalmurzina D.F.1, Shavalieva Z.I.1, Gaskarova E.R.1, Galiullina G.S.1, Safina R.M.1, Tutaeva A.A.1, Khamitova L.I.1
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Affiliations:
- Bashkir State Medical University
- Issue: Vol 28, No 3 (2025)
- Pages: 147-161
- Section: Review
- URL: https://journals.rcsi.science/1560-9537/article/view/381394
- DOI: https://doi.org/10.17816/MSER690503
- EDN: https://elibrary.ru/IHQRUU
- ID: 381394
Cite item
Abstract
Dorsopathies and chronic pain are conditions that represent medical and social challenges due to their high prevalence, tendency toward chronicity, and the limited effectiveness of standard therapeutic approaches, ultimately leading to decreased work capacity and disability in the population. Conventional rehabilitation programs face multiple constraints, including geographic barriers, low availability of specialized care — particularly in rural regions — and insufficient patient adherence. The relevance of this review lies in the need to identify new, more effective and accessible strategies for rehabilitation that incorporate digital and telemedicine technologies (DTT). Based on the analysis of 70 eligible publications according to PRISMA criteria, a comprehensive review was conducted to evaluate the effectiveness of DTT in the rehabilitation of patients with dorsopathies and chronic pain. Based on the available data, various forms of DTT — synchronous (videoconsultations) and asynchronous (mobile applications, SMS reminders, VR/AR technologies, wearable devices based on biofeedback principles) — demonstrate effectiveness comparable to in-person rehabilitation in reducing pain intensity (according to visual analog scale data), improving physical performance (according to Oswestry and Roland–Morris indices), enhancing treatment adherence (up to 90%), and improving quality of life assessed using the SF-36 scale. Key mechanisms of positive DTT effects include reduction of kinesiophobia through graded virtual exposure, modulation of neuroplasticity, and optimization of movement patterns via real-time biofeedback. Despite existing organizational, regulatory, and technological gaps in the Russian Federation (lack of reimbursement frameworks within compulsory health insurance, software licensing challenges, risks of data privacy violations, low digital literacy), both international and Russian evidence supports the high potential for integrating DTT into rehabilitation programs.
About the authors
Aydar M. Zakiev
Bashkir State Medical University
Author for correspondence.
Email: zakiev.am.2026@inbox.ru
ORCID iD: 0009-0003-3174-693X
Russian Federation, Ufa
Adelya R. Yusupova
Bashkir State Medical University
Email: adelulya1@gmail.com
ORCID iD: 0009-0004-7414-4645
Russian Federation, Ufa
Diana M. Khalfieva
Bashkir State Medical University
Email: khalfieva.diana@yandex.ru
ORCID iD: 0009-0005-0608-2996
SPIN-code: 5671-6094
Russian Federation, Ufa
Viliya R. Khuzina
Bashkir State Medical University
Email: khuzina.viliya@mail.ru
ORCID iD: 0009-0002-7713-6929
Russian Federation, Ufa
Dilbar F. Kalmurzina
Bashkir State Medical University
Email: ohakii333@gmail.com
ORCID iD: 0009-0006-8356-5104
Russian Federation, Ufa
Zarina I. Shavalieva
Bashkir State Medical University
Email: z-shavalieva@mail.ru
ORCID iD: 0009-0006-5712-3900
Russian Federation, Ufa
Elvina R. Gaskarova
Bashkir State Medical University
Email: elvinagaskarova2002@mail.ru
ORCID iD: 0009-0007-1559-8622
Russian Federation, Ufa
Gulnara S. Galiullina
Bashkir State Medical University
Email: gulnara227228@gmail.com
ORCID iD: 0009-0000-8627-1933
Russian Federation, Ufa
Renata M. Safina
Bashkir State Medical University
Email: Rene.s9804@xmail.ru
ORCID iD: 0009-0000-1089-2442
Russian Federation, Ufa
Anastasiia A. Tutaeva
Bashkir State Medical University
Email: tutaeva807@mail.ru
ORCID iD: 0009-0004-5502-8841
Russian Federation, Ufa
Laysan I. Khamitova
Bashkir State Medical University
Email: lyaysan.khamitova.98@list.ru
ORCID iD: 0009-0003-9549-8760
Russian Federation, Ufa
References
- Denisov IN, Zaugolnikova TV, Popova TS, Morozova TE. Dorsopathies: routine checkups as a procedure necessary for early diagnostics, risk factors and comorbidities identification. Bulletin of Russian State Medical University. 2018;(5):14–20. doi: 10.24075/vrgmu.2018.065 EDN: YTNQYP
- Konchugova TV, Agasarov LG, Apkhanova TV, Marfina TV. Effective scheme of sequential application of electrical stimulation courses in dorsopathies: comparative study results. Bulletin of rehabilitation medicine. 2025;24(3):38–44. doi: 10.38025/2078-1962-2025-24-3-38-44 EDN: IZTHOG
- Kochubey AV, Kononokhina AK, Burtsev AK. Trends in the Prevalence of Diseases of the Musculoskeletal System and Connective Tissue among the Adult Population of Moscow. Problems of Social Hygiene, Health Care, and Medical History. 2018;26(2):72–77. doi: 10.18821/0869-866Х-2018-26-2-72-77
- Isamukhametova Y. Effectiveness and Perspectives on The Application of Traditional Korean And Western Medicine in The Treatment of Lumbosacral Dorsopathy. International Journal of Medical Sciences And Clinical Research. 2025;5(05):79–87. doi: 10.37547/ijmscr/Volume05Issue05-17
- Vlasova VN. Digitalization of the healthcare system in Russia: upcoming trends and risks. Medical ethics. 2021;9(3):4–8. doi: 10.24075/medet.2021.021 EDN: CVXSGV
- Zabolotnaya NV, Gatilova IN, Zabolotny AT. Digitalization of health: achievements and prospects for development. Economics. Information technologies. 2020;47(2):380–389. doi: 10.18413/2687-0932-2020-47-2-380-389 EDN: BLGEKW
- El-Tallawy SN, Pergolizzi JV, Vasiliu-Feltes I, et al. Innovative Applications of Telemedicine and Other Digital Health Solutions in Pain Management: A Literature Review. Pain and Therapy. 2024;13:791–812. doi: 10.1007/s40122-024-00620-7
- Nikolaev VA, Vorobtsova ES, Nikolaev AA. Digital health in medical rehabilitation after stroke: management of telemedicine technologies. Manager zdravoohranenia. 2024;(11):97–109. doi: 10.21045/1811-0185-2024-11-97-109 EDN: RXMHBG
- Park C, Yi C, Choi WJ, et al. Long-term effects of deep-learning digital therapeutics on pain, movement control, and preliminary cost-effectiveness in low back pain: a randomized controlled trial. Digital Health. 2023;9:20552076231217817. doi: 10.1177/20552076231217817
- Franchini M, Salvatori M, Denoth F, et al. Participation in Low Back Pain Management: It Is Time for the To-Be Scenarios in Digital Public Health. International Journal of Environmental Research and Public Health. 2022;19(13):7805. doi: 10.3390/ijerph19137805
- Volkova OA, Budarin SS, Smirnova EV, Elbek YuV. Experience of using telemedicine technologies in healthcare systems of foreign countries and the Russian Federation: systematic review. Farmakoekonomika. Modern pharmacoeconomics and pharmacoepidemiology. 2021;14(4):549–562. doi: 10.17749/2070-4909/farmakoekonomika.2021.109 EDN: PUDDIN
- Sevostyanova EV, Nikolaev YuA, Bogdankevich NV, et al. Combined rehabilitation in the patients presenting with dorsopathies of the lumbar spine and concomitant irritable bowel syndrome based at a therapeutic clinic. Problems of balneology, physiotherapy, and exercise therapy. 2018;95(2):10–18. doi: 10.17116/kurort201895210-18 EDN: XOBXSX
- Shebib R, Bailey JF, Smittenaar P, et al. Randomized controlled trial of a 12-week digital care program in improving low back pain. NPJ Digital Medicine. 2019;2:1. doi: 10.1038/s41746-018-0076-7
- Toelle TR, Utpadel-Fischler DA, Haas KK, et al. App-based multidisciplinary back pain treatment versus combined physiotherapy plus online education: a randomized controlled trial. NPJ Digital Medicine. 2019;2:34. doi: 10.1038/s41746-019-0109-x
- Garcia LM, Birckhead BJ, Krishnamurthy P, et al. An 8-Week Self-Administered At-Home Behavioral Skills-Based Virtual Reality Program for Chronic Low Back Pain: Double-Blind, Randomized, Placebo-Controlled Trial Conducted During COVID-19. Journal of Medical Internet Research. 2021;23(2):e26292. doi: 10.2196/26292
- Guo Q, Zhang L, Han LL, et al. Effects of Virtual Reality Therapy Combined With Conventional Rehabilitation on Pain, Kinematic Function, and Disability in Patients With Chronic Neck Pain: Randomized Controlled Trial. JMIR Serious Games. 2024;12(1):e42829. doi: 10.2196/42829
- Cui D, Janela D, Costa F, et al. Randomized-Controlled Trial Assessing a Digital Care Program Versus Conventional Physiotherapy for Chronic Low Back Pain. NPJ Digital Medicine. 2023;6(1):121. doi: 10.1038/s41746-023-00870-3
- Abadiyan F, Hadadnezhad M, Khosrokiani Z, et al. Adding a smartphone app to global postural re-education to improve neck pain, posture, quality of life, and endurance in people with nonspecific neck pain: a randomized controlled trial. Trials. 2021;22(1):274. doi: 10.1186/s13063-021-05214-8
- Moreno-Ligero M, Moral-Munoz JA, Salazar A, et al. mHealth Intervention for Improving Pain, Quality of Life, and Functional Disability in Patients With Chronic Pain: Systematic Review. JMIR mHealth and uHealth. 2023;11(1):e40844. doi: 10.2196/40844
- Choi T, Heo S, Choi W, et al. A Systematic Review and Meta-Analysis of the Effectiveness of Virtual Reality-Based Rehabilitation Therapy on Reducing the Degree of Pain Experienced by Individuals With Low Back Pain. International Journal of Environmental Research and Public Health. 2023;20(4):3502. doi: 10.3390/ijerph20043502
- Goudman L, Jansen J, Billot M, et al. Virtual Reality Applications in Chronic Pain Management: Systematic Review and Meta-Analysis. JMIR Serious Games. 2022;10(2):e34402. doi: 10.2196/34402
- Garofano M, Del Sorbo R, Calabrese M, et al. Remote Rehabilitation and Virtual Reality Interventions Using Motion Sensors for Chronic Low Back Pain: A Systematic Review of Biomechanical, Pain, Quality of Life, and Adherence Outcomes. Technologies. 2025;13(5):186. doi: 10.3390/technologies13050186
- Tejera DM, Beltran-Alacreu H, Cano-de-la-Cuerda R, et al. Effects of Virtual Reality versus Exercise on Pain, Functional, Somatosensory and Psychosocial Outcomes in Patients with Non-Specific Chronic Neck Pain: A Randomized Clinical Trial. International Journal of Environmental Research and Public Health. 2020;17(16):5950. doi: 10.3390/ijerph17165950
- Özden F, Özkeskin M, Tümtürk İ, et al. The effect of exercise and education combination via telerehabilitation in patients with chronic neck pain: a randomized controlled trial. International Journal of Medical Informatics. 2023;180:105281. doi: 10.1016/j.ijmedinf.2023.105281
- Afzal MW, Ahmad A, Hanif HMB, et al. Effects of Virtual Reality Exercises on Chronic Low Back Pain: Quasi-Experimental Study. JMIR Rehabilitation and Assistive Technologies. 2023;10:e43985. doi: 10.2196/43985
- Lara-Palomo IC, Antequera-Soler E, Matarán-Peñarrocha GA, et al. Comparison of the effectiveness of an e-health program versus a home rehabilitation program in patients with chronic low back pain: a double blind randomized controlled trial. Digital Health. 2022;8:20552076221074482. doi: 10.1177/20552076221074482
- Christiansen S, Cohen SP. Chronic Pain: Pathophysiology and Mechanisms. In: Singh V, Falco FJ, Kaye AD, et al., editors. Essentials of Interventional Techniques in Managing Chronic Pain. Springer, Cham; 2024. doi: 10.1007/978-3-031-46217-7_2
- Vergne-Salle P, Bertin P. Chronic pain and neuroinflammation. Joint Bone Spine. 2021;88(6):105222. doi: 10.1016/j.jbspin.2021.105222
- Opara JA, Saulicz E, Szczygieł JW, et al. Is the Central Sensitization in Chronic Nonspecific Low Back Pain Structural Phenomenon or Psychological Reaction? A Narrative Review. Journal of Clinical Medicine. 2025;14(2):577. doi: 10.3390/jcm14020577
- Li XH, Miao HH, Zhuo M. NMDA Receptor Dependent Long-Term Potentiation in Chronic Pain. Neurochemical Research. 2019;44(3):531–538. doi: 10.1007/s11064-018-2614-8
- Kopach O, Voitenko N. Spinal AMPA receptors: amenable players in central sensitization for chronic pain therapy? Channels. 2021;15(1):284–297. doi: 10.1080/19336950.2021.1885836
- Palada V, Ahmed AS, Finn A, et al. Characterization of neuroinflammation and periphery-to-CNS inflammatory cross-talk in patients with disc herniation and degenerative disc disease. Brain, Behavior, and Immunity. 2019;75:60–71. doi: 10.1016/j.bbi.2018.09.010
- Loggia ML. “Neuroinflammation”: Does It Have a Role in Chronic Pain? Evidence From Human Imaging. Pain. 2024;165(11S):S58–S67. doi: 10.1097/j.pain.0000000000003342
- Tao ZY, Wang PX, Wei SQ, et al. The Role of Descending Pain Modulation in Chronic Primary Pain: Potential Application of Drugs Targeting Serotonergic System. Neural Plasticity. 2019;2019(1):1389296. doi: 10.1155/2019/1389296
- Moreira LPC, Mendoza C, Barone M, et al. Reduction in Pain Inhibitory Modulation and Cognitive-Behavioral Changes in Patients With Chronic Low Back Pain: A Case-Control Study. Pain Management Nursing. 2021;22(5):599–604. doi: 10.1016/j.pmn.2021.05.004
- Macías-Toronjo I, Rojas-Ocaña MJ, Sánchez-Ramos JL, et al. Pain catastrophizing, kinesiophobia and fear-avoidance in non-specific work-related low-back pain as predictors of sickness absence. PLOS One. 2020;15(12):e0242994. doi: 10.1371/journal.pone.0242994
- De Lucia A, Perlini C, Chiarotto A, et al. eHealth-Integrated Psychosocial and Physical Interventions for Chronic Pain in Older Adults: Scoping Review. Journal of Medical Internet Research. 2024;26:e55366. doi: 10.2196/55366
- Eccleston C, Fisher E, Liikkanen S, et al. A prospective, double-blind, pilot, randomized, controlled trial of an “embodied” virtual reality intervention for adults with low back pain. Pain. 2022;163(9):1700–1715. doi: 10.1097/j.pain.0000000000002617
- Jaffal SM. Neuroplasticity in chronic pain: insights into diagnosis and treatment. The Korean Journal of Pain. 2025;38(2):89–102. doi: 10.3344/kjp.24393
- Zou J, Hao S. Exercise-induced neuroplasticity: a new perspective on rehabilitation for chronic low back pain. Frontiers in Molecular Neuroscience. 2024;17:1407445. doi: 10.3389/fnmol.2024.1407445
- Pratscher S, Mickle AM, Marks JG, et al. Optimizing Chronic Pain Treatment with Enhanced Neuroplastic Responsiveness: A Pilot Randomized Controlled Trial. Nutrients. 2021;13(5):1556. doi: 10.3390/nu13051556
- Bazzari AH, Bazzari FH. Advances in targeting central sensitization and brain plasticity in chronic pain. Egyptian Journal of Neurology, Psychiatry and Neurosurgery. 2022;58:38. doi: 10.1186/s41983-022-00472-y
- Maggio MG, Bonanno M, Calderone A, et al. Remapping Body Representation Using Virtual Reality in Chronic Neuropathic Pain: Systematic Review. Journal of Medical Internet Research. 2025;27:e71074. doi: 10.2196/71074
- Trujillo MS, Alvarez AF, Nguyen L, et al. Embodiment in virtual reality for the treatment of chronic low back pain: a case series. Journal of Pain Research. 2020;13:3131–3137. doi: 10.2147/JPR.S275312
- Sakuma S, Kimpara K, Kawai Y, et al. Integrating Physical Therapy and Virtual Reality to Manage Pain-Related Fear of Movement in Patients With Chronic Pain: A Randomized Controlled Trial. Cureus. 2025;17(2):e79551. doi: 10.7759/cureus.79551
- Hennessy RW, Rumble D, Christian M, et al. A graded exposure, locomotion-enabled virtual reality app during walking and reaching for individuals with chronic low back pain: cohort gaming design. JMIR Serious Games. 2020;8(3):e17799. doi: 10.2196/17799
- Peebles AT, Van der Veen S, Stamenkovic A, et al. A virtual reality game suite for graded rehabilitation in patients with low back pain and a high fear of movement: within-subject comparative study. JMIR Serious Games. 2022;10(1):e32027. doi: 10.2196/32027
- Simons LE, Hess CW, Choate ES, et al. Virtual Reality–Augmented Physiotherapy for Chronic Pain in Youth: Protocol for a Randomized Controlled Trial Enhanced With a Single-Case Experimental Design. JMIR Research Protocols. 2022;11(12):e40705. doi: 10.2196/40705
- Albakri G, Bouaziz R, Alharthi W, et al. Phobia Exposure Therapy Using Virtual and Augmented Reality: A Systematic Review. Applied Sciences. 2022;12(3):1672. doi: 10.3390/app12031672
- Albakri G, Bouaziz R, Alharthi W, et al. Phobia Exposure Therapy Using Virtual and Augmented Reality: A Systematic Review. Applied Sciences. 2022;12(3):1672. doi: 10.3390/app12031672
- Alsubaie AM, Martinez-Valdes E, De Nunzio AM, et al. Trunk control during repetitive sagittal movements following a real-time tracking task in people with chronic low back pain. Journal of Electromyography and Kinesiology. 2021;57:102533. doi: 10.1016/j.jelekin.2021.102533
- Liikkanen S, Mäkinen M, Huttunen T, et al. Body movement as a biomarker for use in chronic pain rehabilitation: an embedded analysis of an RCT of a virtual reality solution for adults with chronic pain. Frontiers in Pain Research. 2022;3:1085791. doi: 10.3389/fpain.2022.1085791
- Yao R, Zhang W, Evans R, et al. Inequities in Health Care Services Caused by the Adoption of Digital Health Technologies: Scoping Review. Journal of Medical Internet Research. 2022;24(3):e34144. doi: 10.2196/34144
- Kugusheva TV, Laskova TS, Paykova VA. Telemedicine technology management: strategic priorities and institutional barriers. State and municipal management. Scholar notes. 2025;(1):43–55. doi: 10.22394/2079-1690-2025-1-1-43-55 EDN: LZKLUZ
- Beckers R, Kwade Z, Zanca F. The EU medical device regulation: Implications for artificial intelligence-based medical device software in medical physics. Physica Medica. 2021;83:1–8. doi: 10.1016/j.ejmp.2021.02.011
- Gerke S, Babic B, Evgeniou T, et al. The need for a system view to regulate artificial intelligence/machine learning-based software as medical device. NPJ Digital Medicine. 2020;3:53. doi: 10.1038/s41746-020-0262-2
- Ruzanova VD, Kryukova ES. The principle of confidentiality in the context of medical industry modernization: a systemic legal approach. Tomsk state university journal. 2024;(507):248–254. doi: 10.17223/15617793/507/28 EDN: MHHZEM
- Voshev DV, Vosheva NA, Shepel RN, Son IM, Drapkina OM. Comparative analysis of the use of electronic internet of things technologies in the healthcare sector of foreign countries and Russia. Manager Zdravoochranenia.. 2023;(8):44–53. doi: 10.21045/1811-0185-2023-8-44-53 EDN: KBFHTM
- Sainimnuan S, Preedachitkul R, Petchthai P, et al. Low Prevalence of Adequate eHealth Literacy and Willingness to Use Telemedicine Among Older Adults: Cross-Sectional Study From a Middle-Income Country. Journal of Medical Internet Research. 2025;27:e65380. doi: 10.2196/65380
- Shaderkin IA. Telemedicine barriers and ways to overcome them. Russian journal of telemedicine and e-healthcare. 2022;8(2):59–76. doi: 10.29188/2712-9217-2022-8-2-59-76 EDN: SOXZRL
- Manakina ES, Medvedeva OV, Kazaeva OV, Tazina TV. Digital transformation of private health: integration features. Modern healthcare and medical statistics issues. 2022;(5):632–644. doi: 10.24412/2312-2935-2022-5-632-644 EDN: NKHMMR
- Mittal A. Digital Health: Data Privacy and Security with Cloud Computing. Issues in Information Systems. 2020;21(1):227–238. doi: 10.48009/1_iis_2020_227-23
- Alhammad N, Alajlani M, Abd-Alrazaq A, et al. Patients’ Perspectives on the Data Confidentiality, Privacy, and Security of mHealth Apps: Systematic Review. Journal of Medical Internet Research. 2024;26:e50715. doi: 10.2196/50715
- Nurgalieva L, O’Callaghan D, Doherty G. Security and Privacy of mHealth Applications: A Scoping Review. IEEE Access. 2020;8:104247–104268. doi: 10.1109/ACCESS.2020.2999934
- Voshev DV. Improving primary health care using digital technologies: methodology for developing tools for assessing “digital maturity” and scientifically based recommendations. Manager zdravoohranenia. 2024;(10):53–62. doi: 10.21045/1811-0185-2024-10-53-62 EDN: WUHXDX
- Esina EA, Kalitskaya VV, Rykalina OA, Kolobov EA. The role of digital technologies in optimizing healthcare costs: challenges and opportunities. Bulletin of the Academy of knowledge. 2024;5(64):182–187. EDN: DQBNNH
- Grigorieva NS, Demkina AE, Korobeynikova AN. Digitalization in the Russian healthcare: barriers to digital maturity. Population and Economics. 2024;8(1):1–14. doi: 10.3897/popecon.8.e111793 EDN: AKZFIN
- Lebedeva DA. Comparative analysis of effective data protection practices in healthcare: Russia and international standards. RUDN Journal of Law. 2025;29(1):235–254. doi: 10.22363/2313-2337-2025-29-1-235-254 EDN: RYZIXU
- McGraw D, Mandl KD. Privacy protections to encourage use of health-relevant digital data in a learning health system. NPJ Digital Medicine. 2021;4(1):2. doi: 10.1038/s41746-020-00362-8
- Rzhevskaia N, Lapina M, Babenko M. A study of efficiency of data protection in the electronic healthcare field. Legal Informatics. 2024;(3):68–85. doi: 10.24412/1994-1404-2024-3-68-85 EDN: DZQVDC
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