Мақаланы E-mail арқылы жіберу Study by inverse gas chromatography of the solubility of rifabutin in water in the presence of cyclodextrin
- Авторлар: Anshakova A.V.1, Konyukhov V.Y.1
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Мекемелер:
- Dmitry Mendeleev University of Chemical Technology of Russia
- Шығарылым: Том 90, № 2 (2017)
- Беттер: 209-213
- Бөлім: Physicochemical Studies of Systems and Processes
- URL: https://journals.rcsi.science/1070-4272/article/view/214707
- DOI: https://doi.org/10.1134/S1070427217020082
- ID: 214707
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Аннотация
Inverse gas chromatography was used to study the stability of rifabutin and cyclodextrin complexes in water. The thermodynamic mixing functions were determined in the system rifabutin‒cyclodextrin‒water. Addition of hydroxypropyl-β-cyclodextrin to rifabutin creates in water a thermodynamically stable complex, with the solubility of rifabutin in water thereby raised and this antibiotic made more bioavailable in curing of tuberculosis.
Авторлар туралы
A. Anshakova
Dmitry Mendeleev University of Chemical Technology of Russia
Хат алмасуға жауапты Автор.
Email: anshakova_a@mail.ru
Ресей, ul. Miusskaya 9, Moscow, 125047
V. Konyukhov
Dmitry Mendeleev University of Chemical Technology of Russia
Email: anshakova_a@mail.ru
Ресей, ul. Miusskaya 9, Moscow, 125047
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