Pyrazoles and Isoxazoles Based Sulfanilamide and Phenazone as Antimicrobial Agents: Synthesis and Biological Activity
- 作者: Moustafa A.1, El-Sayed H.1, El Rayes S.1, Morsy H.2, Abd-allah S.3, Ismail H.1, Abd El-Aal M.1
-
隶属关系:
- Department of Chemistry, Faculty of Science
- Higher Institution of Engineering & Modern Technology
- Department of Biochemistry, Faculty of Medicine
- 期: 卷 89, 编号 11 (2019)
- 页面: 2314-2320
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/223179
- DOI: https://doi.org/10.1134/S1070363219110240
- ID: 223179
如何引用文章
详细
New pyrazole and pyridine derivatives have been synthesized from sulfanilamide and phenazone via diazotization and coupling with a wide range of α-CH acids followed by heterocyclization with hydrazine derivative, hydroxylamine and cyanoacetamide. The antimicrobial tests of the products demonstrate high to moderate activity against Gram (−ve) bacteria and the tested fungi. No positive action of the products is observed against Gram (+ve) bacteria.
作者简介
A. Moustafa
Department of Chemistry, Faculty of Science
编辑信件的主要联系方式.
Email: ah_hu_mostafa@yahoo.com
埃及, Zagazig, 44519
H. El-Sayed
Department of Chemistry, Faculty of Science
Email: ah_hu_mostafa@yahoo.com
埃及, Zagazig, 44519
S. El Rayes
Department of Chemistry, Faculty of Science
Email: ah_hu_mostafa@yahoo.com
埃及, Ismailia, 41522
H. Morsy
Higher Institution of Engineering & Modern Technology
Email: ah_hu_mostafa@yahoo.com
埃及, Elmarg, Cairo, 13774
S. Abd-allah
Department of Biochemistry, Faculty of Medicine
Email: ah_hu_mostafa@yahoo.com
埃及, Zagazig, 44519
H. Ismail
Department of Chemistry, Faculty of Science
Email: ah_hu_mostafa@yahoo.com
埃及, Ismailia, 41522
M. Abd El-Aal
Department of Chemistry, Faculty of Science
Email: ah_hu_mostafa@yahoo.com
埃及, Ismailia, 41522
![](/img/style/loading.gif)