Synthesis, Structure, and Biological Activity of Copper and Cobalt Coordination Compounds with Substituted 2-(2-Hydroxybenzylidene)-N-(prop-2-en-1-yl)hydrazinecarbothioamides
- 作者: Burduniuc O.1,2, Tsapkov V.3, Rudic V.4, Gulea A.3, Graur V.3, Chumakov Y.5,6, Petrenko P.5, Balan G.1
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隶属关系:
- Testemitanu State University of Medicine and Pharmacy
- National Agency of Public Health
- State University of Moldova
- Institute of Microbiology and Biotechnology
- Institute of Applied Physics
- Gebze Institute of Technology
- 期: 卷 89, 编号 5 (2019)
- 页面: 953-964
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222906
- DOI: https://doi.org/10.1134/S1070363219050153
- ID: 222906
如何引用文章
详细
The reaction of N-(prop-2-en-1-yl)hydrazinecarbothioamide with substituted 2-hydroxybenzaldehydes afforded the corresponding Schiff bases which were used as ligands to obtain copper and cobalt coordination compounds Cu(NL1–6)X · n H2O (X = Cl−, \(\rm{NO}_3^-\); n = 0–3), Co(HL2)2NO3, and Co(NL6)2Cl. The structure of the isolated complexes was determined by NMR spectroscopy and X-ray analysis. The complexes were tested for antimicrobial and antifungal activity against S. aureus, E. coli, and yeast-like fungi. Inhibitory effect of the initial thioamides and their complexes against human myeloid leukemia HL-60 cancer cell line was also studied.
作者简介
O. Burduniuc
Testemitanu State University of Medicine and Pharmacy; National Agency of Public Health
Email: vtsapkov@gmail.com
摩尔多瓦共和国, Kishinev; Kishinev
V. Tsapkov
State University of Moldova
编辑信件的主要联系方式.
Email: vtsapkov@gmail.com
摩尔多瓦共和国, ul. Mateevicha 60, Kishinev
V. Rudic
Institute of Microbiology and Biotechnology
Email: vtsapkov@gmail.com
摩尔多瓦共和国, Kishinev
A. Gulea
State University of Moldova
Email: vtsapkov@gmail.com
摩尔多瓦共和国, ul. Mateevicha 60, Kishinev
V. Graur
State University of Moldova
Email: vtsapkov@gmail.com
摩尔多瓦共和国, ul. Mateevicha 60, Kishinev
Yu. Chumakov
Institute of Applied Physics; Gebze Institute of Technology
Email: vtsapkov@gmail.com
摩尔多瓦共和国, Kishinev; Gebze/Kocaeli, Çayirova
P. Petrenko
Institute of Applied Physics
Email: vtsapkov@gmail.com
摩尔多瓦共和国, Kishinev
G. Balan
Testemitanu State University of Medicine and Pharmacy
Email: vtsapkov@gmail.com
摩尔多瓦共和国, Kishinev
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