Synthesis, Antimicrobial, and Antioxidant Studies of Some New Indolo[3,2-c]isoquinoline Derivatives
- 作者: Verma V.1
-
隶属关系:
- Department of Chemistry
- 期: 卷 88, 编号 12 (2018)
- 页面: 2628-2645
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222608
- DOI: https://doi.org/10.1134/S1070363218120265
- ID: 222608
如何引用文章
详细
As a part of systematic study, new series of 6-{[5-(5-substituted 2-phenyl-1H-indol-3-yl)- methyleneamino]-1,3,4-oxadiazol-2-yl}-8-substituted-6H-indolo[3,2-c]isoquinolin-5(11H)-ones and their derivatives are synthesized and evaluated for their biological activities. Compound 8a displays potent antimicrobial activity against bacteria E. coli, K. penumoniae, and S. aureus, and fungi A. niger, A. flavus, and A. fumigates. Compounds 7a and 8a demonstrate promising radical scavenging and chelating with ferrous ions (Fe2+). According to the accumulated data the designed motifs exhibit higher biological activities than the reference compounds.
作者简介
Vaijinath Verma
Department of Chemistry
编辑信件的主要联系方式.
Email: drvermachem@gmail.com
印度, Shahabad, Kalaburagi, Karnataka, 585228