Synthesis of Phosphorus-Containing Podands―Analogs of Diglycolamide Based on Diphenyl- and Dibutylphosphorylmethanol under Phase Transfer Catalysis Conditions
- 作者: Kharlamov A.1, Belus S.1, Artyushin O.2, Bondarenko N.1
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隶属关系:
- Institute of Chemicals and High Purity Compounds
- Nesmeyanov Institute of Organolement Compounds
- 期: 卷 88, 编号 9 (2018)
- 页面: 1842-1849
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222411
- DOI: https://doi.org/10.1134/S107036321809013X
- ID: 222411
如何引用文章
详细
A convenient method for preparation of phosphorus-containing podands R2P(O)CH2OCH2X, where X = C(O)NBu2; P(O)R′2, R = R′ = Ph, Bu, R = Ph, R′ = Bu via OH-alkylation of phosphorylmethanols under the phase transfer conditions in the presence of Cs2CO3 was developed. Carbamoyl-substituted dimethyl ethers were synthesized via transformation of phosphorylmethanols to phosphorylmethoxyacetic acids, followed by amidation. Symmetrical bisphosphoryl substituted dimethyl ethers were obtained by reaction of phosphorylmethanols with tosyl chloride in the presence of Cs2CO3. The synthesis of unsymmetrical substituted ether in the presence of Cs2CO3 was complicated by transesterification of phosphorylmethyl tosylate resulting in the formation of symmetrical dimethyl ethers as byproducts.
作者简介
A. Kharlamov
Institute of Chemicals and High Purity Compounds
Email: bond039@mail.ru
俄罗斯联邦, Bogorodskii val 3, Moscow, 107076
S. Belus
Institute of Chemicals and High Purity Compounds
Email: bond039@mail.ru
俄罗斯联邦, Bogorodskii val 3, Moscow, 107076
O. Artyushin
Nesmeyanov Institute of Organolement Compounds
Email: bond039@mail.ru
俄罗斯联邦, Moscow
N. Bondarenko
Institute of Chemicals and High Purity Compounds
编辑信件的主要联系方式.
Email: bond039@mail.ru
俄罗斯联邦, Bogorodskii val 3, Moscow, 107076
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