Synthesis of Phosphorus-Containing Podands―Analogs of Diglycolamide Based on Diphenyl- and Dibutylphosphorylmethanol under Phase Transfer Catalysis Conditions
- Авторлар: Kharlamov A.1, Belus S.1, Artyushin O.2, Bondarenko N.1
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Мекемелер:
- Institute of Chemicals and High Purity Compounds
- Nesmeyanov Institute of Organolement Compounds
- Шығарылым: Том 88, № 9 (2018)
- Беттер: 1842-1849
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222411
- DOI: https://doi.org/10.1134/S107036321809013X
- ID: 222411
Дәйексөз келтіру
Аннотация
A convenient method for preparation of phosphorus-containing podands R2P(O)CH2OCH2X, where X = C(O)NBu2; P(O)R′2, R = R′ = Ph, Bu, R = Ph, R′ = Bu via OH-alkylation of phosphorylmethanols under the phase transfer conditions in the presence of Cs2CO3 was developed. Carbamoyl-substituted dimethyl ethers were synthesized via transformation of phosphorylmethanols to phosphorylmethoxyacetic acids, followed by amidation. Symmetrical bisphosphoryl substituted dimethyl ethers were obtained by reaction of phosphorylmethanols with tosyl chloride in the presence of Cs2CO3. The synthesis of unsymmetrical substituted ether in the presence of Cs2CO3 was complicated by transesterification of phosphorylmethyl tosylate resulting in the formation of symmetrical dimethyl ethers as byproducts.
Авторлар туралы
A. Kharlamov
Institute of Chemicals and High Purity Compounds
Email: bond039@mail.ru
Ресей, Bogorodskii val 3, Moscow, 107076
S. Belus
Institute of Chemicals and High Purity Compounds
Email: bond039@mail.ru
Ресей, Bogorodskii val 3, Moscow, 107076
O. Artyushin
Nesmeyanov Institute of Organolement Compounds
Email: bond039@mail.ru
Ресей, Moscow
N. Bondarenko
Institute of Chemicals and High Purity Compounds
Хат алмасуға жауапты Автор.
Email: bond039@mail.ru
Ресей, Bogorodskii val 3, Moscow, 107076