p-Aromatic Isothiocyanates: Synthesis and Anti Plant Pathogen Activity
- 作者: Tang J.1, Niu J.1, Wang W.1, Huo H.1, Li J.1, Luo L.1, Cao Y.1
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隶属关系:
- College of Plant Protection
- 期: 卷 88, 编号 6 (2018)
- 页面: 1252-1257
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222273
- DOI: https://doi.org/10.1134/S1070363218060348
- ID: 222273
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详细
In this study, a series of p-aromatic isothiocyanates are prepared by reacting p-aromatic amines with carbon disulphide and further treating with molecular iodine to yield corresponding isothiocyanate derivatives. The structures of newly synthesized compounds are confirmed by IR, NMR, and MS data. Activity of the products against plant pathogenic fungi and bacteria is tested and the structure-activity relationship is approached. p-Nitrophenyl isothiocyanate most efficiently inhibits Rhizoctonia solani and Erwinia carotovora. The order of seven aromatic isothiocyanates antifungicidal activity is following: p-nitrophenyl > p-methoxyphenyl > p-chlorophenyl > p-methylphenyl > p-ethylphenyl > phenyl > p-fluorophenyl. For antibacterial activity, the order was p-nitrophenyl > p-chlorophenyl > p-methylphenyl > p-ethylphenyl > p-fluorophenyl > phenyl > p-methoxyphenyl. The present study indicates that some of the compounds exhibit promising antimicrobial activity and can be used as an alternative to the traditional synthetic fungicides for controlling R. solani and E. carotovora.
作者简介
J. Tang
College of Plant Protection
Email: caoysong@126.com
中国, Beijing, 100193
J. Niu
College of Plant Protection
Email: caoysong@126.com
中国, Beijing, 100193
W. Wang
College of Plant Protection
Email: caoysong@126.com
中国, Beijing, 100193
H. Huo
College of Plant Protection
Email: caoysong@126.com
中国, Beijing, 100193
J. Li
College of Plant Protection
Email: caoysong@126.com
中国, Beijing, 100193
L. Luo
College of Plant Protection
Email: caoysong@126.com
中国, Beijing, 100193
Y. Cao
College of Plant Protection
编辑信件的主要联系方式.
Email: caoysong@126.com
中国, Beijing, 100193
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