Isatin Derivatives Containing Sterically Hindered Phenolic Fragment and Water-Soluble Acyl Hydrazones on Their Basis: Synthesis and Antimicrobial Activity
- 作者: Bogdanov A.1, Zaripova I.2, Voloshina A.1, Strobykina A.1, Kulik N.1, Bukharov S.2, Mironov V.1
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隶属关系:
- A.E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
- Kazan National Research Technological University
- 期: 卷 88, 编号 1 (2018)
- 页面: 57-67
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/221942
- DOI: https://doi.org/10.1134/S1070363218010097
- ID: 221942
如何引用文章
详细
Condensation reactions of isatin derivatives with 3,5-di(tert-butyl)-4-hydroxybenzyl acetate and the Girard’s reagent T has afforded a series of novel water-soluble isatin-3-acyl hydrazones containing a sterically hindered phenolic fragment in position 1 of the heterocycle; antimicrobial activity of the products has been estimated. It has been shown that the isatin derivatives with bromine or methoxy substituent in the benzo fragment as well as the acyl hydrazones containing 5-methyl or 5-ethyl group are the most active against Staphylococcus aureus and Bacillus cereus.
作者简介
A. Bogdanov
A.E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
编辑信件的主要联系方式.
Email: abogdanov@inbox.ru
俄罗斯联邦, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088
I. Zaripova
Kazan National Research Technological University
Email: abogdanov@inbox.ru
俄罗斯联邦, Kazan, Tatarstan
A. Voloshina
A.E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: abogdanov@inbox.ru
俄罗斯联邦, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088
A. Strobykina
A.E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: abogdanov@inbox.ru
俄罗斯联邦, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088
N. Kulik
A.E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: abogdanov@inbox.ru
俄罗斯联邦, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088
S. Bukharov
Kazan National Research Technological University
Email: abogdanov@inbox.ru
俄罗斯联邦, Kazan, Tatarstan
V. Mironov
A.E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: abogdanov@inbox.ru
俄罗斯联邦, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088
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