Synthesis of New Functionalized 1,4-Dihydroquinolines and Pyrimido[4,5-b]quinolines
- 作者: Khoramdelan F.1, Davoodnia A.1, Bozorgmehr M.1, Ebrahimi M.1
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隶属关系:
- Department of Chemistry, Mashhad Branch
- 期: 卷 87, 编号 12 (2017)
- 页面: 2961-2965
- 栏目: Letters to the Editor
- URL: https://journals.rcsi.science/1070-3632/article/view/221785
- DOI: https://doi.org/10.1134/S1070363217120386
- ID: 221785
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详细
The reaction of N-alkylisatoic anhydrides with malononitrile in pyridine led to formation of new 2-amino-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carbonitriles. Following treatment of these compounds with an excess of aliphatic carboxylic acids in the presence of POCl3 under reflux gave novel 2,10-dialkylpyrimido[4,5-b]quinoline-4,5(3H,10H)-diones with high yields. It is probable that synthesis of the latter products proceed via the tandem intramolecular Pinner–Dimroth rearrangement. All synthesized compounds were characterized by spectral and microanalytical data.
作者简介
F. Khoramdelan
Department of Chemistry, Mashhad Branch
Email: adavoodnia@mshdiau.ac.ir
伊朗伊斯兰共和国, Mashhad, 9175687119
A. Davoodnia
Department of Chemistry, Mashhad Branch
编辑信件的主要联系方式.
Email: adavoodnia@mshdiau.ac.ir
伊朗伊斯兰共和国, Mashhad, 9175687119
M. Bozorgmehr
Department of Chemistry, Mashhad Branch
Email: adavoodnia@mshdiau.ac.ir
伊朗伊斯兰共和国, Mashhad, 9175687119
M. Ebrahimi
Department of Chemistry, Mashhad Branch
Email: adavoodnia@mshdiau.ac.ir
伊朗伊斯兰共和国, Mashhad, 9175687119