Synthesis of New Functionalized 1,4-Dihydroquinolines and Pyrimido[4,5-b]quinolines
- Autores: Khoramdelan F.1, Davoodnia A.1, Bozorgmehr M.1, Ebrahimi M.1
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Afiliações:
- Department of Chemistry, Mashhad Branch
- Edição: Volume 87, Nº 12 (2017)
- Páginas: 2961-2965
- Seção: Letters to the Editor
- URL: https://journals.rcsi.science/1070-3632/article/view/221785
- DOI: https://doi.org/10.1134/S1070363217120386
- ID: 221785
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Resumo
The reaction of N-alkylisatoic anhydrides with malononitrile in pyridine led to formation of new 2-amino-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carbonitriles. Following treatment of these compounds with an excess of aliphatic carboxylic acids in the presence of POCl3 under reflux gave novel 2,10-dialkylpyrimido[4,5-b]quinoline-4,5(3H,10H)-diones with high yields. It is probable that synthesis of the latter products proceed via the tandem intramolecular Pinner–Dimroth rearrangement. All synthesized compounds were characterized by spectral and microanalytical data.
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Sobre autores
F. Khoramdelan
Department of Chemistry, Mashhad Branch
Email: adavoodnia@mshdiau.ac.ir
Irã, Mashhad, 9175687119
A. Davoodnia
Department of Chemistry, Mashhad Branch
Autor responsável pela correspondência
Email: adavoodnia@mshdiau.ac.ir
Irã, Mashhad, 9175687119
M. Bozorgmehr
Department of Chemistry, Mashhad Branch
Email: adavoodnia@mshdiau.ac.ir
Irã, Mashhad, 9175687119
M. Ebrahimi
Department of Chemistry, Mashhad Branch
Email: adavoodnia@mshdiau.ac.ir
Irã, Mashhad, 9175687119