The new green procedure for pyrazolopyrimidinone based dihydropyrimidinones and their antibacterial screening
- 作者: Allam M.1, Bhavani A.1, Vodnala S.1
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隶属关系:
- Department of Chemistry
- 期: 卷 87, 编号 11 (2017)
- 页面: 2712-2718
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/221637
- DOI: https://doi.org/10.1134/S1070363217110299
- ID: 221637
如何引用文章
详细
A series of novel hybrid aza heterocycles containing pyrazolopyrimidinone and dihydropyrimidinone scaffolds was developed using Cu(II) catalyzed Biginelli condensation as an efficient, new green synthetic method under mild and solvent free conditions. Pyrazolopyrimidinone based aldehydes, alkyl acetoacetates and urea/thiourea were used as the components in the reaction to afford hybrid aza heterocycles in high to excellent yields. The products were screened for in vitro antibacterial activity and all of those demonstrated high to excellent activity.
作者简介
Muralidhar Allam
Department of Chemistry
Email: durgabhavani237@gmail.com
印度, Hyderabad, Telangana, 500007
A. Bhavani
Department of Chemistry
编辑信件的主要联系方式.
Email: durgabhavani237@gmail.com
印度, Hyderabad, Telangana, 500007
Sumathi Vodnala
Department of Chemistry
Email: durgabhavani237@gmail.com
印度, Hyderabad, Telangana, 500007