Supramolecular inclusion complexes of β-cyclodextrin with 4-(acyloxy)-4-(cyclopropylethynyl)-1-(2-ethoxyethyl)piperidines
- 作者: Seilkhanov T.1, Iskakova T.2, Zhumakova S.3, Bimurzayeva T.2, Seilkhanov O.1, Nazarenko L.1, Praliev K.2
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隶属关系:
- Sh. Ualikhanov Kokshetau State University
- Bekturov Institute of Chemical Sciences
- Kazakh–British Technical University
- 期: 卷 87, 编号 2 (2017)
- 页面: 270-275
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/218322
- DOI: https://doi.org/10.1134/S1070363217020190
- ID: 218322
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详细
4-Acyloxy-4-(cyclopropylethynyl)-1-(2-ethoxyethyl)piperidines have been synthesized by reaction of 1-(2-ethoxyethyl)piperidin-4-one with cyclopropylacetylene and subsequent acylation of intermediate 4-(cyclopropylethynyl)piperidin-4-ol. The resulting esters react with β-cyclodextrin to give supramolecular inclusion complexes. The complexation is accompanied by inclusion of the N-ethoxyethyl fragment of one substrate molecule in the inner cavity of one receptor molecule. The structure of 4-acyloxy-4-(cyclopropylethynyl-1-(2-ethoxyethyl)piperidines and their inclusion complexes with cyclodextrin has been studied by NMR spectroscopy.
作者简介
T. Seilkhanov
Sh. Ualikhanov Kokshetau State University
编辑信件的主要联系方式.
Email: tseilkhanov@mail.ru
哈萨克斯坦, ul. Abaya 76, Kokshetau, 020000
T. Iskakova
Bekturov Institute of Chemical Sciences
Email: tseilkhanov@mail.ru
哈萨克斯坦, ul. Ualikhanova 106, Almaty, 050010
S. Zhumakova
Kazakh–British Technical University
Email: tseilkhanov@mail.ru
哈萨克斯坦, ul. Tole bi 59, Almaty, 050000
T. Bimurzayeva
Bekturov Institute of Chemical Sciences
Email: tseilkhanov@mail.ru
哈萨克斯坦, ul. Ualikhanova 106, Almaty, 050010
O. Seilkhanov
Sh. Ualikhanov Kokshetau State University
Email: tseilkhanov@mail.ru
哈萨克斯坦, ul. Abaya 76, Kokshetau, 020000
L. Nazarenko
Sh. Ualikhanov Kokshetau State University
Email: tseilkhanov@mail.ru
哈萨克斯坦, ul. Abaya 76, Kokshetau, 020000
K. Praliev
Bekturov Institute of Chemical Sciences
Email: tseilkhanov@mail.ru
哈萨克斯坦, ul. Ualikhanova 106, Almaty, 050010