Synthesis, characterization, and antimicrobial activity of some chiral linear carboxamides with incorporated peptide linkage
- 作者: Khalifa N.1,2, Amr A.1,3, Al-Omar M.1, Nossier E.4
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隶属关系:
- Pharmaceutical Chemistry Department, Drug Exploration & Development Chair, College of Pharmacy
- Theripeutical Chemistry Department
- Applied Organic Chemistry Department
- Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)
- 期: 卷 86, 编号 12 (2016)
- 页面: 2785-2790
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/216936
- DOI: https://doi.org/10.1134/S1070363216120409
- ID: 216936
如何引用文章
详细
A new group of chiral linear 7-methyl-4-oxo-1,8-naphthyridine-3-carboxamides with incorporated peptide linkage have been synthesized via condensation of 1-ethyl-N-(1-hydrazinyl-3-methyl-1-oxobutan-2-yl)-7-methyl–4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide with various derivatives of sugar pentose, acetophenones and thiosemicarbazide. Structures of the products were elucidated by spectroscopic methods and chemical analysis. Antimicrobial properties of the synthesized compounds were tested.
作者简介
N. Khalifa
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair, College of Pharmacy; Theripeutical Chemistry Department
编辑信件的主要联系方式.
Email: nagykhalifa@hotmail.com
沙特阿拉伯, Riyadh, 11451; Dokki, Cairo, 12622
A. Amr
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair, College of Pharmacy; Applied Organic Chemistry Department
Email: nagykhalifa@hotmail.com
沙特阿拉伯, Riyadh, 11451; Dokki, Cairo, 12622
M. Al-Omar
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair, College of Pharmacy
Email: nagykhalifa@hotmail.com
沙特阿拉伯, Riyadh, 11451
E. Nossier
Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)
Email: nagykhalifa@hotmail.com
埃及, Cairo