Synthesis and reactivity of 4-hydroxy-5-methyl-2-(2-oxo-2H-chromen-3-yl)-6H-1,3-oxazin-6-ones
- 作者: Chernov N.1, Filippova P.1, Yakovlev I.1, Zakhs V.1, Belyakov A.2
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隶属关系:
- St. Petersburg State Chemical Pharmaceutical Academy
- St. Petersburg State Institute of Technology (Technical University)
- 期: 卷 86, 编号 6 (2016)
- 页面: 1292-1299
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/215251
- DOI: https://doi.org/10.1134/S1070363216060128
- ID: 215251
如何引用文章
详细
4-Hydroxy-6H-1,3-oxazin-6-ones with a coumarin fragment in position 2 of the oxazine ring were synthesized. Their hydrolysis, alcoholysis, and hydrazinolysis afforded a number of new coumarin derivatives containing malonamic acid and 1,2,4-triazole residues. The low stability of the title compounds toward oxygencentered nucleophiles was interpreted by quantum chemical calculations.
作者简介
N. Chernov
St. Petersburg State Chemical Pharmaceutical Academy
编辑信件的主要联系方式.
Email: nikita.chernov@pharminnotech.com
俄罗斯联邦, ul. Professora Popova 14/A, St. Petersburg, 197376
P. Filippova
St. Petersburg State Chemical Pharmaceutical Academy
Email: nikita.chernov@pharminnotech.com
俄罗斯联邦, ul. Professora Popova 14/A, St. Petersburg, 197376
I. Yakovlev
St. Petersburg State Chemical Pharmaceutical Academy
Email: nikita.chernov@pharminnotech.com
俄罗斯联邦, ul. Professora Popova 14/A, St. Petersburg, 197376
V. Zakhs
St. Petersburg State Chemical Pharmaceutical Academy
Email: nikita.chernov@pharminnotech.com
俄罗斯联邦, ul. Professora Popova 14/A, St. Petersburg, 197376
A. Belyakov
St. Petersburg State Institute of Technology (Technical University)
Email: nikita.chernov@pharminnotech.com
俄罗斯联邦, Moskovskii pr. 26, St. Petersburg, 190013