Synthesis and biological activity of new hybrids compounds derived from benzofuroxanes and polyene antibiotics
- 作者: Chugunova E.1, Mukhamatdinova R.2, Sazykina M.3, Sazykin I.3, Khammami M.3, Akylbekov N.2, Burilov A.1, Kulik N.1, Zobov V.1
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隶属关系:
- Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Centre
- Kazan State Technological University
- Ivanovskii Academy of Biology and Biotechnology
- 期: 卷 86, 编号 5 (2016)
- 页面: 1037-1040
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/214924
- DOI: https://doi.org/10.1134/S1070363216050091
- ID: 214924
如何引用文章
详细
Hybrid compounds based on 4,6-dichloro-5-nitrobenzofuroxan, 7-chloro-4,6-dinitrobenzofuroxan, 5,7-dichloro-4,6-dinitrobenzofuroxan, and polyene antibiotics (amphotericin B and nystatin) have been prepared for the first time. They have exhibited biological activity comparable to that of starting antibiotics. Activity of the compound derived from 5,7-dichloro-4,6-dinitrobenzofuroxan and nystatin towards Trichophyton mentagrophytes is 4 times higher than that of nystatin.
作者简介
E. Chugunova
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Centre
编辑信件的主要联系方式.
Email: elena-chugunova@list.ru
俄罗斯联邦, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088
R. Mukhamatdinova
Kazan State Technological University
Email: elena-chugunova@list.ru
俄罗斯联邦, Kazan, Tatarstan
M. Sazykina
Ivanovskii Academy of Biology and Biotechnology
Email: elena-chugunova@list.ru
俄罗斯联邦, Rostov-on-Don
I. Sazykin
Ivanovskii Academy of Biology and Biotechnology
Email: elena-chugunova@list.ru
俄罗斯联邦, Rostov-on-Don
M. Khammami
Ivanovskii Academy of Biology and Biotechnology
Email: elena-chugunova@list.ru
俄罗斯联邦, Rostov-on-Don
N. Akylbekov
Kazan State Technological University
Email: elena-chugunova@list.ru
俄罗斯联邦, Kazan, Tatarstan
A. Burilov
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Centre
Email: elena-chugunova@list.ru
俄罗斯联邦, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088
N. Kulik
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Centre
Email: elena-chugunova@list.ru
俄罗斯联邦, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088
V. Zobov
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Centre
Email: elena-chugunova@list.ru
俄罗斯联邦, ul. Akademika Arbuzova 8, Kazan, Tatarstan, 420088