N,N -Di(prop-2-yn-1-yl)adamantan-1-amines in 1,3-Dipolar Cycloaddition Reactions with Azide-Containing Pharmacophores

V. B. Sokolov; A. Yu. Aksinenko

doi:10.1134/S1070363219080280

N,N-Di(prop-2-yn-1-yl)adamantan-1-amines in 1,3-Dipolar Cycloaddition Reactions with Azide-Containing Pharmacophores

Авторы: Sokolov V.¹, Aksinenko A.¹
Учреждения:
1. Institute of Physiologically Active Substances of the Russian Academy of Sciences
Выпуск: Том 89, № 8 (2019)
Страницы: 1724-1727
Раздел: Letters to the Editor
URL: https://journals.rcsi.science/1070-3632/article/view/223054
DOI: https://doi.org/10.1134/S1070363219080280
ID: 223054

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Аннотация
Об авторах
Список литературы
Статистика

Аннотация

A synthetic approach to combining pharmacophore ligands with an aminoadamantyl-containing spacer based on a copper-catalyzed alkyne-azide 1,3-dipolar cycloaddition of N,N-di(prop-2-yne-1-yl)adamantan-1-amines and azido-containing carbazole, tetrahydrocarbazole, phenothiazine and adamantan-2-amine derivatives was proposed.

Ключевые слова

N,N-di(prop-2-yn-1-yl)adamantan-1-amines, carbazole, tetrahydrocarbazole, phenothiazine, adamantan-2-amine, 1,3-dipolar cycloaddition

Об авторах

V. Sokolov

Institute of Physiologically Active Substances of the Russian Academy of Sciences

Email: alaks@ipac.ac.ru
Россия, Severnyi proezd 1, Chernogolovka, 142432

A. Aksinenko