Отправить статью по E-mail Synthesis and Biological Evaluation of Amide Derivatives of Imidazopyridine as Anticancer Agents
- Авторы: Ramesh V.1, Rao G.1, Ramachandran D.1, Chakravarthy A.2
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Учреждения:
- Department of Chemistry
- Integrated Product Development
- Выпуск: Том 89, № 7 (2019)
- Страницы: 1491-1495
- Раздел: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222999
- DOI: https://doi.org/10.1134/S1070363219070193
- ID: 222999
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Аннотация
A series of new amide derivatives of imidazopyridine is synthesized and structures of the products are confirmed by 1H and 13C NMR, and mass spectral data. The synthesized derivatives are screened for their anticancer activity against four human cancer cell lines: lung cancer (A549), breast cancer (MCF-7), melanoma cancer (A375), and colon cancer (HT-29). Six synthesized compounds exhibit more potent activity than the control drug.
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Об авторах
V. Ramesh
Department of Chemistry
Автор, ответственный за переписку.
Email: vramesh.chem1@gmail.com
Индия, Guntur, Andhra Pradesh
G. Rao
Department of Chemistry
Email: vramesh.chem1@gmail.com
Индия, Guntur, Andhra Pradesh
D. Ramachandran
Department of Chemistry
Email: vramesh.chem1@gmail.com
Индия, Guntur, Andhra Pradesh
A. Chakravarthy
Integrated Product Development
Email: vramesh.chem1@gmail.com
Индия, Bachupally, Hyderabad
