Enviar artigo por via de e-mail Synthesis and Biological Evaluation of Amide Derivatives of Imidazopyridine as Anticancer Agents
- Autores: Ramesh V.1, Rao G.1, Ramachandran D.1, Chakravarthy A.2
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Afiliações:
- Department of Chemistry
- Integrated Product Development
- Edição: Volume 89, Nº 7 (2019)
- Páginas: 1491-1495
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222999
- DOI: https://doi.org/10.1134/S1070363219070193
- ID: 222999
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Resumo
A series of new amide derivatives of imidazopyridine is synthesized and structures of the products are confirmed by 1H and 13C NMR, and mass spectral data. The synthesized derivatives are screened for their anticancer activity against four human cancer cell lines: lung cancer (A549), breast cancer (MCF-7), melanoma cancer (A375), and colon cancer (HT-29). Six synthesized compounds exhibit more potent activity than the control drug.
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Sobre autores
V. Ramesh
Department of Chemistry
Autor responsável pela correspondência
Email: vramesh.chem1@gmail.com
Índia, Guntur, Andhra Pradesh
G. Rao
Department of Chemistry
Email: vramesh.chem1@gmail.com
Índia, Guntur, Andhra Pradesh
D. Ramachandran
Department of Chemistry
Email: vramesh.chem1@gmail.com
Índia, Guntur, Andhra Pradesh
A. Chakravarthy
Integrated Product Development
Email: vramesh.chem1@gmail.com
Índia, Bachupally, Hyderabad
