On the Two-Route Mechanism of the Reaction of 1-Alkenes with EtMgX Catalyzed by TaCl5

Аннотация

The reaction of 1-alkenes with C₂D₅MgBr in the presence of TaCl₅ has been studied. Basing on the distribution of the deuterium label in the alkyl chain of the regioisomeric organomagnesium compounds, a tentative mechanism of their formation as key intermediates of 3-substituted tantalocyclopentanes has been proposed. The energy profiles of the reactions of carbomagnesation and β-reductive magnesaethylation of 1-alkenes have been obtained using the DFT method.