Derivatives of furyl(diethoxyphosphoryl)acetic aldehyde in Wittig reaction
- Авторы: Pevzner L.1
-
Учреждения:
- St. Petersburg State Institute of Technology (Technical University)
- Выпуск: Том 87, № 7 (2017)
- Страницы: 1516-1526
- Раздел: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/220672
- DOI: https://doi.org/10.1134/S107036321707012X
- ID: 220672
Цитировать
Аннотация
Reactions of furyl(diethoxyphosphoryl)acetic aldehyde containing ester or cyano group in the furan ring with ethoxycarbonylmethylenetriphenylphosphorane has been shown to afford alkyl E-4-(furyl)-4-(diethoxyphosphoryl)but-3(2)-enoates. When treated with potassium tert-butoxide the mixture of alkyl E-4-(3-ethoxycarbonylfur-2-yl)-4-(diethoxyphosphoryl)but-2-enoate and -but-3-enoate gives a potassium salt of CHacid. Its acidifying results in a mixture of starting compounds with a larger amount of -but-3-enoate. Under analogous conditions the mixture of alkyl E-4-(2-ethoxycarbonylfur-3-yl)-4-(diethoxyphosphoryl)but-2-enoate and -but-3-enoate undergoes cyclization to a phosphorylated derivative of alkyl 7-hydroxybenzofuran-6-carboxylate. The cyclization of the mixture of alkyl E-4-(4-ethoxycarbonylfur-3-yl)-4-(diethoxyphosphoryl)but-2-enoate and -but-3-enoate gives analogous derivative of isobenzofuran.
Об авторах
L. Pevzner
St. Petersburg State Institute of Technology (Technical University)
Автор, ответственный за переписку.
Email: pevzner_lm@list.ru
Россия, Moskovskii pr. 26, St. Petersburg, 190031
![](/img/style/loading.gif)