Отправить статью по E-mail Synthesis and characterization of new pyrazolyl-substituted thiazolidinone, thiazole, and thiazoline candidates
- Авторы: Khalifa N.1,2, Nossier E.3, Al-Omar M.1
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Учреждения:
- Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy
- Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division
- Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)
- Выпуск: Том 87, № 6 (2017)
- Страницы: 1295-1299
- Раздел: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/220391
- DOI: https://doi.org/10.1134/S1070363217060263
- ID: 220391
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Аннотация
1-(3-Chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazole-4-carbaldehyde was used in preparation of (E)-1-{[1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazol-4-yl]methylene}thiosemicarbazide. Its following reaction with ethyl bromoacetate, diethyl 2-bromomalonate, phenacyl bromide, and maleic anhydride gave pyrazolyl pharmacophore linked thiazole, thiazoline and thiazolidinone-5-carboxylic acid derivatives.
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Об авторах
N. Khalifa
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division
Автор, ответственный за переписку.
Email: nagykhalifa@hotmail.com
Саудовская Аравия, Riyadh, 11451; Dokki, Cairo, 12622
E. Nossier
Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)
Email: nagykhalifa@hotmail.com
Египет, Cairo, 11754
M. Al-Omar
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy
Email: nagykhalifa@hotmail.com
Саудовская Аравия, Riyadh, 11451
