Features of reactions of (E)-1-(β-aroylvinyl)pyridinium bromides with binucleophiles
- Авторы: Khachikyan R.1, Ovakimyan Z.1, Panosyan G.1, Tamazyan R.1, Ayvazyan A.1
-
Учреждения:
- Institute of Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
- Выпуск: Том 86, № 7 (2016)
- Страницы: 1574-1580
- Раздел: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/215639
- DOI: https://doi.org/10.1134/S1070363216070070
- ID: 215639
Цитировать
Аннотация
Regardless of pH and a solvent nature the reactions of (E)-1-(β-aroylvinyl)pyridinium bromides with hydrazine led to the formation of pyrazole derivatives. The salts reacted with thiourea via intermediate formation of 4-arylpyrimidine-2-thiol to give (Z)-2-[(β-aroylvinyl)sulfanyl]-4-arylpyrimidines. In the case of N,N'-diphenylthiourea the reaction provided 6-aryl-3-aroyl-1-phenylpyridinium bromides. Pyridine hydrobromide liberated in the reaction course has a major influence on the process chemoselectivity.
Ключевые слова
Об авторах
R. Khachikyan
Institute of Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Автор, ответственный за переписку.
Email: khachikyanraya@gmail.com
Армения, pr. Azatutyan 26, Yerevan, 0014
Z. Ovakimyan
Institute of Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Email: khachikyanraya@gmail.com
Армения, pr. Azatutyan 26, Yerevan, 0014
G. Panosyan
Institute of Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Email: khachikyanraya@gmail.com
Армения, pr. Azatutyan 26, Yerevan, 0014
R. Tamazyan
Institute of Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Email: khachikyanraya@gmail.com
Армения, pr. Azatutyan 26, Yerevan, 0014
A. Ayvazyan
Institute of Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Email: khachikyanraya@gmail.com
Армения, pr. Azatutyan 26, Yerevan, 0014