Charge-transfer complexes of two highly efficient drugs with σ- and π-acceptors: Spectroscopic, thermal, and surface morphology characteristics


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Аннотация

Considerable attention has recently been devoted to the formation of stable charge-transfer (CT) complexes that result from the reaction of drugs with acceptors. Intermolecular CT interactions of two drugs, barbituratic acid (Bar) and ephedrine hydrochloride (Eph), with different σ- and π-acceptors have been studied stoichiometrically, structurally (IR, Raman, 1H NMR, and UV-Vis spectroscopy), thermally, and morphologically (SEM).

Об авторах

A. Naglah

Department of Pharmaceutical Chemistry, Drug Exploration & Development Chair, College of Pharmacy; Peptide Chemistry Department, Chemical Industries Research Division

Email: msrefat@yahoo.com
Саудовская Аравия, Riyadh, 11451; Dokki, Cairo, 12622

M. Al-Omar

Department of Pharmaceutical Chemistry, Drug Exploration & Development Chair, College of Pharmacy

Email: msrefat@yahoo.com
Саудовская Аравия, Riyadh, 11451

O. Ibrahim

Department of Chemistry, Faculty of Sciences

Email: msrefat@yahoo.com
Саудовская Аравия, Taif, 21974

M. Refat

Department of Chemistry, Faculty of Sciences; Department of Chemistry, Faculty of Science, Port Said

Автор, ответственный за переписку.
Email: msrefat@yahoo.com
Саудовская Аравия, Taif, 21974; Port

A. Adam

Department of Chemistry, Faculty of Sciences

Email: msrefat@yahoo.com
Саудовская Аравия, Taif, 21974

H. Saad

Department of Chemistry, Faculty of Sciences; Department of Chemistry, Faculty of Science

Email: msrefat@yahoo.com
Саудовская Аравия, Taif, 21974; Zagazig

N. El-Metwaly

Chemistry Department, College of Applied Sciences; Chemistry Department, Faculty of Science

Email: msrefat@yahoo.com
Саудовская Аравия, Makkah; Mansoura


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