Synthesis of 3-Thiopropionyl Derivatives of 1,3,4-Benzothiadiazepine as Potential Vasopeptidase Inhibitors


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Resumo

A method of synthesis of 3-thiopropinyl derivatives of 5-oxo-1,3,4-benzothiadiazepine-4-acetic acid, potential antihypertensive drugs, vasopeptidase inhibitors, starting from 2-thiobenzoic acid hydrazide has been elaborated.

Sobre autores

A. Ershov

Institute of Macromolecular Compounds of the Russian Academy of Sciences; St. Petersburg State Institute of Technology (Technical University)

Autor responsável pela correspondência
Email: ershov305@mail.ru
Rússia, Bol’shoi pr. V. O. 31, St. Petersburg, 199004; St. Petersburg

A. Martynenkov

Institute of Macromolecular Compounds of the Russian Academy of Sciences

Email: ershov305@mail.ru
Rússia, Bol’shoi pr. V. O. 31, St. Petersburg, 199004

D. Nasledov

Institute of Macromolecular Compounds of the Russian Academy of Sciences

Email: ershov305@mail.ru
Rússia, Bol’shoi pr. V. O. 31, St. Petersburg, 199004

I. Lagoda

State Research Testing Institute of Military Medicine

Email: ershov305@mail.ru
Rússia, St. Petersburg

A. Yakimanskii

Institute of Macromolecular Compounds of the Russian Academy of Sciences; St. Petersburg State University

Email: ershov305@mail.ru
Rússia, Bol’shoi pr. V. O. 31, St. Petersburg, 199004; St. Petersburg


Declaração de direitos autorais © Pleiades Publishing, Ltd., 2019

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