Enviar artigo por via de e-mail A Simple “Green” Synthesis of Novel Bis(3-aryl-1,8-naphthyridin-2-yl)sulfanes and 2-(Methylthio)-3-aryl-1,8-naphthyridines under Microwave Irradiation and Conventional Conditions
- Autores: Ravi D.1, Ashok K.1, Rambabu S.1, Sakram B.1, Shyam P.2
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Afiliações:
- Department of Chemistry
- Biomedical Informatics Center
- Edição: Volume 88, Nº 6 (2018)
- Páginas: 1232-1237
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222268
- DOI: https://doi.org/10.1134/S1070363218060312
- ID: 222268
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Resumo
An eco-friendly and highly efficient synthesis of substituted bis(3-aryl-1,8-naphthyridin-2-yl)-sulfanes and 2-(methylthio)-3-aryl-1,8-naphthyridines under microwave and conventional conditions. The products are obtained with high yields and purity within short reaction time. The synthesized derivatives are screened for anti-microbial activity against bacteria and fungi. Molecular docking of the synthesized compounds with DNA Gyrase is studied.
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Sobre autores
D. Ravi
Department of Chemistry
Email: bschemou@gmail.com
Índia, Hyderabad, Telangana State, 500007
K. Ashok
Department of Chemistry
Email: bschemou@gmail.com
Índia, Hyderabad, Telangana State, 500007
S. Rambabu
Department of Chemistry
Email: bschemou@gmail.com
Índia, Hyderabad, Telangana State, 500007
B. Sakram
Department of Chemistry
Autor responsável pela correspondência
Email: bschemou@gmail.com
Índia, Hyderabad, Telangana State, 500007
P. Shyam
Biomedical Informatics Center
Email: bschemou@gmail.com
Índia, Tarnaka, Hyderabad, 500007
