Email this article A Simple “Green” Synthesis of Novel Bis(3-aryl-1,8-naphthyridin-2-yl)sulfanes and 2-(Methylthio)-3-aryl-1,8-naphthyridines under Microwave Irradiation and Conventional Conditions
- Authors: Ravi D.1, Ashok K.1, Rambabu S.1, Sakram B.1, Shyam P.2
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Affiliations:
- Department of Chemistry
- Biomedical Informatics Center
- Issue: Vol 88, No 6 (2018)
- Pages: 1232-1237
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222268
- DOI: https://doi.org/10.1134/S1070363218060312
- ID: 222268
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Abstract
An eco-friendly and highly efficient synthesis of substituted bis(3-aryl-1,8-naphthyridin-2-yl)-sulfanes and 2-(methylthio)-3-aryl-1,8-naphthyridines under microwave and conventional conditions. The products are obtained with high yields and purity within short reaction time. The synthesized derivatives are screened for anti-microbial activity against bacteria and fungi. Molecular docking of the synthesized compounds with DNA Gyrase is studied.
About the authors
D. Ravi
Department of Chemistry
Email: bschemou@gmail.com
India, Hyderabad, Telangana State, 500007
K. Ashok
Department of Chemistry
Email: bschemou@gmail.com
India, Hyderabad, Telangana State, 500007
S. Rambabu
Department of Chemistry
Email: bschemou@gmail.com
India, Hyderabad, Telangana State, 500007
B. Sakram
Department of Chemistry
Author for correspondence.
Email: bschemou@gmail.com
India, Hyderabad, Telangana State, 500007
P. Shyam
Biomedical Informatics Center
Email: bschemou@gmail.com
India, Tarnaka, Hyderabad, 500007
