Synthesis of Methyl-Substituted Derivatives of 5-Hydroxy-6-methyluracil

S. F. Petrova; T. R. Nugumanov; A. N. Lobov; L. V. Spirikhin; Yu. I. Murinov; S. P. Ivanov

doi:10.1134/S1070363218010231

Synthesis of Methyl-Substituted Derivatives of 5-Hydroxy-6-methyluracil

Autores: Petrova S.¹, Nugumanov T.¹, Lobov A.¹, Spirikhin L.¹, Murinov Y.¹, Ivanov S.¹
Afiliações:
1. Ufa Institute of Chemistry
Edição: Volume 88, Nº 1 (2018)
Páginas: 136-139
Seção: Letters to the Editor
URL: https://journals.rcsi.science/1070-3632/article/view/221970
DOI: https://doi.org/10.1134/S1070363218010231
ID: 221970

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5-Hydroxy-3,6-dimethyluracil, 5-methoxy-1,3,6-trimethyluracil, earlier unknown 5-methoxy-6- methyluracil, 5-methoxy-1,6-dimethyluracil, and 5-methoxy-3,6-dimethyluracil have been synthesized via alkylation of 5-hydroxy-6-methyluracil with dimethylsulfate in aqueous-alkaline media. The obtained compounds have been identified using ¹Н, ¹³С, and ¹⁵N NMR spectroscopy.