Enviar artigo por via de e-mail Synthesis and biological activity of hydrazones of o- and p-hydroxybenzoic acids. Spatial structure of 5-Bromo-2-hydroxybenzylidene-4-hydroxybenzohydrazide
- Autores: Nurkenov O.1, Satpaeva Z.1, Schepetkin I.2,3, Khlebnikov A.4,5, Turdybekov K.6, Seilkhanov T.7, Fazylov S.1
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Afiliações:
- Institute of Organic Synthesis and Coal Chemistry of Kazakhstan
- Montana State University
- Russian-Speaking Academic Science Association (RASA) Center
- National Research Tomsk Polytechnic University
- Polzunov Altai State Technical University
- Buketov Karaganda State University
- Ualikhanov Kokshetau State University
- Edição: Volume 87, Nº 10 (2017)
- Páginas: 2299-2306
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/221403
- DOI: https://doi.org/10.1134/S1070363217100097
- ID: 221403
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Resumo
A series of hydrazones based on hydrazides of o- and p-hydroxybenzoic acids have been prepared. N-(5-Bromo-2-hydroxybenzylidene)-4-hydroxybenzohydrazide has been studied by X-ray diffraction analysis; its molecule forms hydrogen bond with a solvating ethanol molecule. Biological activity of the synthesized hydrazones towards cathepsin Е and(or) elastase of human neutrophils has been determined.
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Sobre autores
O. Nurkenov
Institute of Organic Synthesis and Coal Chemistry of Kazakhstan
Autor responsável pela correspondência
Email: nurkenov_oral@mail.ru
Cazaquistão, ul. Alikhanova 1, Karaganda, 100008
Zh. Satpaeva
Institute of Organic Synthesis and Coal Chemistry of Kazakhstan
Email: nurkenov_oral@mail.ru
Cazaquistão, ul. Alikhanova 1, Karaganda, 100008
I. Schepetkin
Montana State University; Russian-Speaking Academic Science Association (RASA) Center
Email: nurkenov_oral@mail.ru
Estados Unidos da América, Bozeman; Tomsk
A. Khlebnikov
National Research Tomsk Polytechnic University; Polzunov Altai State Technical University
Email: nurkenov_oral@mail.ru
Rússia, Tomsk; Barnaul
K. Turdybekov
Buketov Karaganda State University
Email: nurkenov_oral@mail.ru
Cazaquistão, Karaganda
T. Seilkhanov
Ualikhanov Kokshetau State University
Email: nurkenov_oral@mail.ru
Cazaquistão, Kokshetau
S. Fazylov
Institute of Organic Synthesis and Coal Chemistry of Kazakhstan
Email: nurkenov_oral@mail.ru
Cazaquistão, ul. Alikhanova 1, Karaganda, 100008
