Synthesis of hydrazone derivatives of benzofuran and their antibacterial and antifungal activity
- Autores: Subhashini N.1, Janaki P.1, Bhadraiah B.1
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Afiliações:
- Department of Chemistry, University College of Science
- Edição: Volume 87, Nº 9 (2017)
- Páginas: 2021-2026
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/221244
- DOI: https://doi.org/10.1134/S1070363217090183
- ID: 221244
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Resumo
A series of benzofuran hydrazones 6a–6n were synthesized from benzofuran aldehyde and substituted aromatic hydrazides 5a–5n. Structures of all compounds were confimed by IR, 1H and 13C NMR, and Mass spectral data. These compounds were evaluated for their antibacterial activity against gram-negative bacteria (Escherichia coli, –ve), gram-positive bacteria (Bacillus Subtillis, +ve), and antifungal activity against Candida albicans. All compounds demonstrated considerable activity against bacteria and fungi.
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Sobre autores
N. Subhashini
Department of Chemistry, University College of Science
Autor responsável pela correspondência
Email: njsubhashini@yahoo.co.in
Índia, Hyderabad, 500007
P. Janaki
Department of Chemistry, University College of Science
Email: njsubhashini@yahoo.co.in
Índia, Hyderabad, 500007
B. Bhadraiah
Department of Chemistry, University College of Science
Email: njsubhashini@yahoo.co.in
Índia, Hyderabad, 500007